Suppr超能文献

使用二维阵列电离室对螺旋断层放射治疗调强放射治疗计划进行剂量验证。

Dose verification of helical tomotherapy intensity modulated radiation therapy planning using 2D-array ion chambers.

作者信息

Xu S, Xie C, Ju Z, Dai X, Gong H, Wang L, Yang J

机构信息

Department of Radiation Oncology, PLA General Hospital, Beijing, China.

出版信息

Biomed Imaging Interv J. 2010 Apr-Jun;6(2):e24. doi: 10.2349/biij.6.2.e24. Epub 2010 Apr 1.

Abstract

PURPOSE

To investigate the clinical usage of dose verification of Helical Tomotherapy plans by using 2D-array ion chambers, and to develop an efficient way to validate the dose delivered for the patients during treatments.

MATERIALS AND METHODS

A pixel-segmented ionisation chamber device, IMRT MatriXX™ and Multicube™ phantom from IBA were used on ten selected Tomotherapy IMRT/IGRT head and neck plans in this study. The combined phantom was set up to measure the dose distribution from coronal and sagittal planes. The setup of phantom was guided for verifying the correction position by pre-treatment Tomotherapy MVCT images. After the irradiation, the measured dose distributions of coronal and sagittal planes were compared with those from calculation by the planning system for cross verification. The results were evaluated by the absolute and relative doses as well as Gamma (γ) function. The feasibility of the different measuring methods was studied for this rotational treatment technique.

RESULTS

The dose distributions measured by the MatriXX 2D array were in good agreements with plans calculated by Tomotherapy planning system. The discrepancy between the measured dose and predicted dose in the selected points was within ±3%. In the comparison of the pixel-segmented ionisation chamber versus treatment planning system using the 3 mm/3% γ-function criteria, the mean passing rates of 2 mm dose grid with γ-parameter ≤1 were 97.37% and 96.91%, in two orthogonal planes (coronal and sagittal directions), respectively.

CONCLUSION

MatriXX with Multicube is a new system created for rotational delivery quality assurance (QA) and found to be reliable to measure both absolute dose and relative dose distributions, simultaneously. It achieves the goal of an efficient and accurate dosimetry validation method of the helical delivery pattern for the Helical Tomotherapy IMRT planning.

摘要

目的

研究使用二维阵列电离室进行螺旋断层放射治疗计划剂量验证的临床应用,并开发一种在治疗期间验证患者所接受剂量的有效方法。

材料与方法

本研究中,对十个选定的断层放射治疗调强放疗/图像引导放疗头颈部计划,使用了像素分割电离室装置、IBA的IMRT MatriXX™和Multicube™模体。组合模体的设置是为了测量冠状面和矢状面的剂量分布。通过治疗前的断层放射治疗兆伏级计算机断层扫描图像指导模体的设置,以验证校正位置。照射后,将测量得到的冠状面和矢状面剂量分布与计划系统计算的剂量分布进行比较,以进行交叉验证。结果通过绝对剂量、相对剂量以及伽马(γ)函数进行评估。针对这种旋转治疗技术,研究了不同测量方法的可行性。

结果

MatriXX二维阵列测量的剂量分布与断层放射治疗计划系统计算的计划结果高度吻合。所选点处测量剂量与预测剂量之间的差异在±3%以内。在使用3毫米/3%γ函数标准比较像素分割电离室与治疗计划系统时,在两个正交平面(冠状面和矢状面方向)中,γ参数≤1的2毫米剂量网格的平均通过率分别为97.37%和96.91%。

结论

MatriXX与Multicube是为旋转放射治疗质量保证(QA)而创建的新系统,发现其可同时可靠地测量绝对剂量和相对剂量分布。它实现了对螺旋断层放射治疗调强放疗计划的螺旋放射模式进行高效、准确剂量测定验证方法的目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/616b/3097769/e12b7283ccb3/biij-06-e24-g01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验