National Hospital Organization Kurihama Medical and Addiction Center, 5-3-1 Nobi, Yokosuka, Kanagawa, 239-0841, Japan.
Lundbeck Japan K.K, Tokyo, Japan.
Qual Life Res. 2020 Jan;29(1):223-235. doi: 10.1007/s11136-019-02310-w. Epub 2019 Oct 4.
The Alcohol Quality of Life Scale (AQoLS) is accepted as a useful measure in assessing impact of alcohol use disorders (AUD) on health-related quality of life (HR-QoL) in Western cultures. We aimed to assess the psychometric properties of the Japanese version of the AQoLS (AQoLS-Japan).
This was a 3-month, observational cohort study in patients undergoing routine treatment for AUD in Japan. HR-QoL was assessed using the AQoLS-Japan (34 items, 7 dimensions). Scale psychometrics were analyzed using correlative techniques.
Data from 132 patients were analyzed. Inter-item and item-scale correlations for the AQoLS-Japan scale were moderate to strong. Confirmatory factor analysis results supported the AQoLS-Japan structure but there was evidence of interdependency among some items and factors. Cronbach's alpha coefficients for internal consistency ranged from 0.73 to 0.97, and intraclass correlation coefficients for scores between test (baseline) and retest (2 weeks) ranged from 0.65 to 0.82. Convergent and divergent validity and known-groups validity were supported. Evaluation of within-group change demonstrated that the AQoLS-Japan total and domains consistently demonstrated statistically significant improvement (p < 0.001 in all cases) in HR-QoL over time. Estimates for minimal clinically important difference on the AQoLS-Japan total score ranged from 13.2 to 18.2 for group-level change and from 2.4 to 15.7 for a group-level difference.
The AQoLS-Japan is a reliable and valid measure of HR-QoL that is able to demonstrate benefits associated with the routine treatment of AUD in Japan.
酒精生活质量量表(AQoLS)在评估酒精使用障碍(AUD)对健康相关生活质量(HR-QoL)的影响方面,被认为是一种有用的衡量标准,在西方文化中得到认可。我们旨在评估日本版 AQoLS(AQoLS-Japan)的心理测量特性。
这是一项在日本接受 AUD 常规治疗的患者中进行的为期 3 个月的观察性队列研究。使用 AQoLS-Japan(34 项,7 个维度)评估 HR-QoL。使用相关技术分析量表心理测量学特性。
对 132 名患者的数据进行了分析。AQoLS-Japan 量表的项目间和项目与量表间的相关性为中等至强。验证性因子分析结果支持 AQoLS-Japan 结构,但有些项目和因子之间存在相互依存关系。内部一致性的克朗巴赫α系数范围为 0.73 至 0.97,测试(基线)和重测(2 周)之间的评分的组内相关系数范围为 0.65 至 0.82。支持了收敛和发散有效性以及已知组有效性。组内变化评估表明,AQoLS-Japan 总分和各领域在 HR-QoL 方面随着时间的推移始终显示出统计学上的显著改善(所有情况下 p < 0.001)。AQoLS-Japan 总分的最小临床重要差异估计值在群组水平的变化中范围为 13.2 至 18.2,在群组水平差异中范围为 2.4 至 15.7。
AQoLS-Japan 是一种可靠且有效的 HR-QoL 衡量标准,能够证明日本 AUD 常规治疗相关的获益。