期待疗法及输卵管通液术治疗子宫内膜异位症相关性不孕

Expectant management and hydrotubations in the treatment of endometriosis-associated infertility.

作者信息

Olive D L, Stohs G F, Metzger D A, Franklin R R

出版信息

Fertil Steril. 1985 Jul;44(1):35-41. doi: 10.1016/s0015-0282(16)48674-7.

Abstract

One hundred twenty-three infertility patients with laparoscopically documented endometriosis were managed expectantly for an interval of 1 to 25 months. Analysis revealed an overall pregnancy rate of 24.4% and a monthly fecundity rate (MFR) of 3.1%. Patients with mild disease had an overall pregnancy rate of 52.9% and an MFR of 5.7%. Women with moderate endometriosis did less well, but still demonstrated a pregnancy rate of 25% and an MFR of 3.2%. No pregnancies occurred with severe disease and expectant management. Postlaparoscopic hydrotubation was evaluated for its therapeutic effect with the use of multivariate analysis and maximum likelihood analysis. The results indicate that there is no decrease in the laparoscopy to conception interval, whereas a potential increase in cure rate cannot be adequately evaluated at this time.

摘要

123例经腹腔镜确诊为子宫内膜异位症的不孕患者接受了1至25个月的期待治疗。分析显示，总体妊娠率为24.4%，月受孕率（MFR）为3.1%。轻度疾病患者的总体妊娠率为52.9%，MFR为5.7%。中度子宫内膜异位症的女性情况稍差，但仍有25%的妊娠率和3.2%的MFR。重度疾病患者接受期待治疗未发生妊娠。通过多变量分析和最大似然分析评估了腹腔镜输卵管通液术的治疗效果。结果表明，从腹腔镜检查到受孕的间隔时间没有缩短，而此时无法充分评估治愈率是否有潜在提高。