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根治性前列腺切除术治疗局限性前列腺癌且不进行盆腔淋巴结清扫术的肿瘤学结局:单中心随访结果。

Oncological Outcome After Radical Prostatectomy without Pelvic Lymph Node Dissection for Localized Prostate Cancer: Follow-up Results in a Single Institution.

机构信息

Department of Urology, University of Occupational and Environmental Health, Kitakyushu City, Japan.

出版信息

Cancer Invest. 2019;37(10):524-530. doi: 10.1080/07357907.2019.1675076. Epub 2019 Oct 10.

Abstract

The oncological benefit of pelvic lymph node dissection (PLND) is still debatable because data on clinical outcomes of radical prostatectomy (RP) without PLND are lacking. In this study, we reported oncological outcome in consecutive 146 patients who underwent RP without PLND. Although 27% of our patients developed biochemical recurrence, the estimated 5-year overall survival rates were 100%, 96.3%, and 95.7% in the low-, intermediate-, and high-risk groups, respectively. These data in our patients were not inferior to those in previous reports that investigated the survivals in patients who received PLND during RP. The therapeutic significance of PLND should be re-evaluated.

摘要

盆腔淋巴结清扫术(PLND)的肿瘤学获益仍存在争议,因为缺乏根治性前列腺切除术(RP)中不进行 PLND 的临床结果数据。在这项研究中,我们报告了连续 146 例接受 RP 而不进行 PLND 的患者的肿瘤学结果。尽管我们的患者中有 27%出现生化复发,但低、中、高危组的 5 年总生存率分别估计为 100%、96.3%和 95.7%。与之前报道的接受 RP 期间接受 PLND 的患者生存率相比,我们患者的数据并不差。PLND 的治疗意义应重新评估。

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