Suppr超能文献

盆腔淋巴结清扫术在前列腺癌治疗中的作用和争议:重点综述。

The role and controversy of pelvic lymph node dissection in prostate cancer treatment: a focused review.

机构信息

Urology Surgery Department, The Second Affiliated Hospital of Kunming Medical University, 243 Dianmian Avenue, Wuhua District, Kunming, 650101, Yunnan, China.

出版信息

World J Surg Oncol. 2024 Feb 26;22(1):68. doi: 10.1186/s12957-024-03344-2.

Abstract

Pelvic lymph node dissection (PLND) is commonly performed alongside radical prostatectomy. Its primary objective is to determine the lymphatic staging of prostate tumors by removing lymph nodes involved in lymphatic drainage. This aids in guiding subsequent treatment and removing metastatic foci, potentially offering significant therapeutic benefits. Despite varying recommendations from clinical practice guidelines across countries, the actual implementation of PLND is inconsistent, partly due to debates over its therapeutic value. While high-quality evidence supporting the superiority of PLND in oncological outcomes is lacking, its role in increasing surgical time and risk of complications is well-recognized. Despite these concerns, PLND remains the gold standard for lymph node staging in prostate cancer, providing invaluable staging information unattainable by other techniques. This article reviews PLND's scope, guideline perspectives, implementation status, oncologic and non-oncologic outcomes, alternatives, and future research needs.

摘要

盆腔淋巴结清扫术 (PLND) 通常与根治性前列腺切除术同时进行。其主要目的是通过切除参与淋巴引流的淋巴结来确定前列腺肿瘤的淋巴分期。这有助于指导后续治疗和清除转移灶,可能带来显著的治疗益处。尽管各国的临床实践指南有不同的建议,但 PLND 的实际实施情况并不一致,部分原因是其治疗价值存在争议。虽然缺乏支持 PLND 在肿瘤学结果方面优越性的高质量证据,但它会增加手术时间和并发症风险的作用是公认的。尽管存在这些担忧,但 PLND 仍然是前列腺癌淋巴结分期的金标准,提供了其他技术无法获得的宝贵分期信息。本文综述了 PLND 的范围、指南观点、实施现状、肿瘤学和非肿瘤学结果、替代方法以及未来的研究需求。

相似文献

3
Pelvic lymph node dissection in prostate cancer.前列腺癌的盆腔淋巴结清扫术
Eur Urol. 2009 Jun;55(6):1251-65. doi: 10.1016/j.eururo.2009.03.012. Epub 2009 Mar 10.

本文引用的文献

8
Pelvic lymph node dissection in high-risk prostate cancer.高危前列腺癌的盆腔淋巴结清扫术
Int Braz J Urol. 2022 Jan-Feb;48(1):54-66. doi: 10.1590/S1677-5538.IBJU.2020.1063.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验