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合成可吸收单丝缝合材料在磷酸盐缓冲盐水中孵育前后的拉伸性能。

Tensile properties of synthetic, absorbable monofilament suture materials before and after incubation in phosphate-buffered saline.

作者信息

Tobias Karen M, Kidd Calvin E, Mulon Pierre-Yves, Zhu Xiaojuan

机构信息

Department of Small Animal Clinical Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, Tennessee.

Department of Large Animal Clinical Sciences (Mulon), University of Tennessee College of Veterinary Medicine, Knoxville, Tennessee.

出版信息

Vet Surg. 2020 Apr;49(3):550-560. doi: 10.1111/vsu.13326. Epub 2019 Oct 9.

DOI:10.1111/vsu.13326
PMID:31599002
Abstract

OBJECTIVE

To compare tensile properties of synthetic, absorbable, monofilament suture material before and after incubation in phosphate-buffered saline (PBS).

STUDY DESIGN

Two sizes (2-0 and 3-0) of Biosyn, Maxon, Monocryl, PDS II, Securocryl, and Securodox were tested.

SAMPLE POPULATION

Ten suture loops per group.

METHODS

Tensile strength, elongation, and modulus of suture loops were measured at baseline and after 7, 14, 21, or 28 days of incubation in PBS.

RESULTS

Size, suture material, and size × suture material interaction influenced maximum breaking load, maximum elongation, and modulus of elasticity. At baseline, 2-0 and 3-0 Maxon had the highest breaking loads (111.67 N and 79.71 N, respectively) for their size, and 2-0 PDSII and 3-0 Securodox had the lowest (68.71 N and 48.73 N, respectively). Maxon 2-0 and 3-0 had the greatest elongations (9.68 mm and 8.45 mm, respectively) for their size, and 2-0 Biosyn and 3-0 Securocryl had the least (7.21 mm and 6.58 mm, respectively). Biosyn 2-0 and 3-0 had the highest modulus. With incubation, Maxon (2-0), PDS II (2-0, 3-0), and Securodox (2-0, 3-0) maintained or gained strength over 4 weeks. Strengths of 2-0 and 3-0 Biosyn and 3-0 Maxon were maintained for 2 weeks, while Monocryl and Securocryl lost 20% to 44% of baseline strength within 1 week and 60% to 72% within 2 weeks. Day 7 strengths of 2-0 Biosyn and 2-0 Monocryl were greater than baseline strength of 2-0 PDS II. Strength of 3-0 Biosyn at day 14 was greater than strength of Monocryl at days 7 and 14 and greater than strength of 3-0 PDS II, 3-0 Securodox, and 3-0 Securocryl at baseline and days 7 and 14.

CONCLUSION

Suture tensile properties varied with suture size, composition, and brand. At baseline, Maxon suture had the greatest strength and elongation, and Biosyn had the greatest stiffness.

CLINICAL SIGNIFICANCE

Tensile strength retention, when reported as a percentage of original strength, provides insufficient information for comparison of suture tensile properties.

摘要

目的

比较合成可吸收单丝缝合材料在磷酸盐缓冲盐水(PBS)中孵育前后的拉伸性能。

研究设计

对两种尺寸(2-0和3-0)的Biosyn、Maxon、Monocryl、PDS II、Securocryl和Securodox进行测试。

样本量

每组10个缝合线环。

方法

在基线以及在PBS中孵育7、14、21或28天后,测量缝合线环的拉伸强度、伸长率和模量。

结果

尺寸、缝合材料以及尺寸×缝合材料的相互作用影响最大断裂载荷、最大伸长率和弹性模量。在基线时,2-0和3-0的Maxon在其尺寸下具有最高的断裂载荷(分别为111.67 N和79.71 N),而2-0的PDSII和3-0的Securodox最低(分别为68.71 N和48.73 N)。2-0和3-0的Maxon在其尺寸下具有最大伸长率(分别为9.68 mm和8.45 mm),而2-0的Biosyn和3-0的Securocryl最小(分别为7.21 mm和6.58 mm)。2-0和3-0的Biosyn具有最高模量。随着孵育,Maxon(2-0)、PDS II(2-0、3-0)和Securodox(2-0、3-0)在4周内保持或增强了强度。2-0和3-0的Biosyn以及3-0的Maxon的强度保持了2周,而Monocryl和Securocryl在1周内损失了20%至44%的基线强度,在2周内损失了60%至72%。2-0的Biosyn和2-0的Monocryl在第7天的强度大于2-0的PDS II的基线强度。3-0的Biosyn在第14天的强度大于Monocryl在第7天和第14天的强度,且大于3-0的PDS II、3-0的Securodox和3-0的Securocryl在基线以及第7天和第14天的强度。

结论

缝合线的拉伸性能因缝合线尺寸、成分和品牌而异。在基线时,Maxon缝合线具有最大强度和伸长率,而Biosyn具有最大刚度。

临床意义

以原始强度的百分比报告拉伸强度保留情况,为比较缝合线拉伸性能提供的信息不足。

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