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用于伤口愈合的电纺医用缝合线:综述

Electrospun Medical Sutures for Wound Healing: A Review.

作者信息

Xu Lin, Liu Yanan, Zhou Wenhui, Yu Dengguang

机构信息

School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.

Shanghai Engineering Technology Research Center for High-Performance Medical Device Materials, Shanghai 200093, China.

出版信息

Polymers (Basel). 2022 Apr 19;14(9):1637. doi: 10.3390/polym14091637.

Abstract

With the increasing demand for wound healing around the world, the level of medical equipment is also increasing, but sutures are still the preferred medical equipment for medical personnel to solve wound closures. Compared with the traditional sutures, the nanofiber sutures produced by combining the preparation technology of drug-eluting sutures have greatly improved both mechanical properties and biological properties. Electrospinning technology has attracted more attention as one of the most convenient and simple methods for preparing functional nanofibers and the related sutures. This review firstly discusses the structural classification of sutures and the performance analysis affecting the manufacture and use of sutures, followed by the discussion and classification of electrospinning technology, and then summarizes the relevant research on absorbable and non-absorbable sutures. Finally, several common polymers and biologically active substances used in creating sutures are concluded, the related applications of sutures are discussed, and the future prospects of electrospinning sutures are suggested.

摘要

随着全球对伤口愈合的需求不断增加,医疗设备水平也在提高,但缝合线仍然是医务人员解决伤口闭合问题的首选医疗设备。与传统缝合线相比,结合药物洗脱缝合线制备技术生产的纳米纤维缝合线在机械性能和生物学性能方面都有了很大提高。静电纺丝技术作为制备功能性纳米纤维及相关缝合线最便捷、简单的方法之一,受到了更多关注。本文综述首先讨论了缝合线的结构分类以及影响缝合线制造和使用的性能分析,接着对静电纺丝技术进行了讨论和分类,然后总结了可吸收和不可吸收缝合线的相关研究。最后,总结了用于制造缝合线的几种常见聚合物和生物活性物质,讨论了缝合线的相关应用,并对静电纺丝缝合线的未来前景提出了建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7da/9105379/4bcde41bd4a7/polymers-14-01637-g008.jpg

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