Humadi Al-Maini Esraa Hameed, Abd Al-Kadir Israa Tailb, Hassan Al-Joboury Enas Abid
Department of Obstetrics and Gynecology, Al-Mustansiriya University, Baghdad, Iraq.
J Pak Med Assoc. 2019 Aug;69(Suppl 3)(8):S55-S58.
To evaluate the relationship between vitamin D deficiency and dysfunctional labour.
The cross-sectional study was conducted in the Department of Obstetrics and Gynaecology, Al-Yarmouk Teaching Hospital, Baghdad, Iraq, from February to October 2016, and comprised primigravida women who presented with active labour after term pregnancies that were 37-42weeks long. Through history, examination and investigations, the patients were evaluated according to the mode of delivery and the prolongation of 1st or 2nd stage of labour. Also, 5ml blood was taken from each subject and centrifuged for the measurement of vitamin D level using enzyme-linked immunosorbent assasy, and to correlate it with the subjects. Data was analysed using SPSS 20.
There were 100 subjects with a mean age of 28.85 } 5.47 years (range: 17-37 years). Of them, 87(87%) had normal vaginal delivery while 13(1`3%) underwent caesarean section. Vitamin D level was significantly higher in patients who had vaginal delivery, 48.7}22.4nmole/L compared to31.9}16.0nmole/L in patients with caesarean section. Normal vitamin D level was significantly associated with vaginal delivery (p<0.001), but there was no significant association between vitamin D and stage of labour (p>0.05).
Low vitamin D may influence the progress of labour and increase the rate of caesarean section.
评估维生素D缺乏与产程异常之间的关系。
本横断面研究于2016年2月至10月在伊拉克巴格达的亚尔穆克教学医院妇产科进行,纳入妊娠37 - 42周足月后进入活跃期分娩的初产妇。通过病史、检查和调查,根据分娩方式及第一产程或第二产程的延长情况对患者进行评估。此外,从每位受试者采集5ml血液,离心后使用酶联免疫吸附测定法测量维生素D水平,并将其与受试者情况进行关联分析。数据采用SPSS 20进行分析。
共有100名受试者,平均年龄为28.85±5.47岁(范围:17 - 37岁)。其中,87例(87%)经阴道正常分娩,13例(13%)行剖宫产。经阴道分娩患者的维生素D水平显著更高,为48.7±22.4纳摩尔/升,而剖宫产患者为31.9±16.0纳摩尔/升。维生素D水平正常与阴道分娩显著相关(p<0.001),但维生素D与产程阶段之间无显著关联(p>0.05)。
低维生素D水平可能影响产程进展并增加剖宫产率。