两例急性粒单核细胞白血病中的4号染色体三体。
Trisomy 4 in two cases of acute myelomonocytic leukemia.
作者信息
Suciu S, Weh H J, Kuse R, Meier C B, Hossfeld D K
机构信息
Department of Oncology-Hematology, Medical University Clinic, Hamburg, Germany.
出版信息
Cancer Genet Cytogenet. 1988 Jul 1;33(1):19-23. doi: 10.1016/0165-4608(88)90044-1.
PMID:3164237
Abstract
Two cases of acute myelocytic leukemia (AML) type M4 with trisomy 4 are presented. In one case trisomy 4 was associated with del(3). Both patients had no history of exposure to mutagenic events. In our material the frequency of trisomy 4-AML is not higher than 1%.
摘要
本文报告了2例伴有4号染色体三体的急性髓细胞白血病（AML）M4型病例。其中1例4号染色体三体与3号染色体缺失相关。两名患者均无接触诱变事件的病史。在我们的病例资料中，4号染色体三体AML的发生率不高于1%。
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