Wang Wenjun, Wu Jiahong, Zhao Xin, You Beian, Li Chuanbao
Department of Emergency, Chest Pain Center.
Department of Radiology.
Medicine (Baltimore). 2019 Oct;98(43):e17662. doi: 10.1097/MD.0000000000017662.
Acute Type-A aortic dissection (AD) is a challenging clinical emergency. Despite advances in diagnosis and surgical techniques, the high surgical mortality rate of the condition persists. As a result of similarities in clinical symptoms, AD can mimic acute myocardial infarction (AMI). In this paper, we report 2 cases of patients with acute AD manifesting as inferior AMI.
Two patients with undetected AD were misdiagnosed with AMI; in such patients, the administration of thrombolytic therapy has disastrous consequences.
The patients were initially diagnosed with AMI in the emergency room, and then diagnosed with AD during catheterization.
The patients were transferred to the cardiac catheterization laboratory for primary coronary angiography. The initial attempt to selectively engage the coronary ostium was unsuccessful. Subsequent computed tomography angiography (CTA) confirmed AD from the aortic root to the abdominal aorta and dissection violations of the coronary ostium. The patients underwent emergency aortic root replacement.
One patient recovered and was discharged 2 weeks later. At a 1-year follow-up examination, CTA indicated that this patient had made a full recovery. The other patient died 6 days after surgery.
As a result of similarities in clinical symptoms, AD can mimic AMI. Rapid diagnosis and treatment of AD is crucial. Difficulty during catheter engagement should raise the suspicion of acute Type-A AD.
急性A型主动脉夹层(AD)是一种具有挑战性的临床急症。尽管在诊断和手术技术方面取得了进展,但该病的手术死亡率仍然很高。由于临床症状相似,AD可能会被误诊为急性心肌梗死(AMI)。在本文中,我们报告了2例表现为下壁AMI的急性AD患者。
2例未被发现患有AD的患者被误诊为AMI;对于此类患者,给予溶栓治疗会带来灾难性后果。
患者最初在急诊室被诊断为AMI,随后在导管插入术期间被诊断为AD。
患者被转至心脏导管插入实验室进行冠状动脉造影。最初选择性进入冠状动脉口的尝试未成功。随后的计算机断层扫描血管造影(CTA)证实从主动脉根部到腹主动脉存在AD,且夹层侵犯了冠状动脉口。患者接受了急诊主动脉根部置换术。
1例患者康复,2周后出院。在1年的随访检查中,CTA显示该患者已完全康复。另1例患者术后6天死亡。
由于临床症状相似,AD可能会被误诊为AMI。AD的快速诊断和治疗至关重要。导管插入困难时应怀疑急性A型AD。