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关于世界卫生组织提出的2030年疥疮目标的数学建模见解。

Insights from mathematical modelling on the proposed WHO 2030 goals for scabies.

作者信息

Marks Michael, McVernon Jodie, Engelman Daniel, Kaldor John, Steer Andrew

机构信息

London School of Hygiene & Tropical Medicine, London, UK.

The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.

出版信息

Gates Open Res. 2019 Sep 20;3:1542. doi: 10.12688/gatesopenres.13064.1. eCollection 2019.

Abstract

Scabies was adopted by the World Health Organization (WHO) as a Neglected Tropical Disease in 2017. There is currently no formal global scabies control programmes or existing WHO guidelines on scabies control although at least two countries, Fiji and Ethiopia, have adopted national approaches to scabies control. In February 2019 WHO held a first Informal Consultation on a Framework for Scabies Control, in part as a response to multiple national requests for guidance on public health management in high disease burden areas. Below we outline control strategies proposed at this meeting and summarise the role that modelling can play in supporting the development of evidence to translate these proposals into formal WHO recommendations and national and global control programmes. Provisional proposals discussed at the WHO Informal Consultation for a scabies control programme include the use of mass drug administration when the community prevalence of scabies is ≥ 10% (generally considered to reflect a childhood prevalence of at least 20%) and the use of intensified case management when the prevalence is below 10%.

摘要

2017年,疥疮被世界卫生组织(WHO)列为被忽视的热带病。目前尚无正式的全球疥疮控制项目,也没有WHO关于疥疮控制的现有指南,不过至少有两个国家,即斐济和埃塞俄比亚,已采取了国家层面的疥疮控制方法。2019年2月,WHO就疥疮控制框架举行了首次非正式磋商会,部分原因是回应多个国家关于高疾病负担地区公共卫生管理指导的请求。以下我们概述此次会议提出的控制策略,并总结建模在支持证据开发以将这些提议转化为WHO正式建议以及国家和全球控制项目方面可发挥的作用。WHO非正式磋商会讨论的疥疮控制项目临时提议包括,当社区疥疮患病率≥10%(一般认为这反映儿童患病率至少为20%)时采用群体药物给药,患病率低于10%时采用强化病例管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dc4/6792349/96aa8a401266/gatesopenres-3-14195-g0000.jpg

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