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瞳孔对光反应中的最小瞳孔及近视影响视盘光晕大小:一项横断面研究。

Minimum pupil in pupillary response to light and myopia affect disk halo size: a cross-sectional study.

作者信息

Zhao Feng, Han Tian, Chen Xun, Chen Zhi, Zheng Ke, Wang Xiaoying, Zhou Xingtao

机构信息

Key Laboratory of Myopia, Ministry of Health, Fudan University, Shanghai, China.

Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.

出版信息

BMJ Open. 2018 Apr 10;8(4):e019914. doi: 10.1136/bmjopen-2017-019914.

Abstract

OBJECTIVES

To evaluate the relationship between pupillary response to light, myopia and disk halo size.

DESIGN

Cross-sectional study.

SETTING

Single refractive surgery centre.

PARTICIPANTS

In this study, 197 right eyes of 197 patients between 20 and 35 years of age were evaluated for disk halo size and pupillary response to light with a vision monitor.

PRIMARY AND SECONDARY OUTCOME MEASURES

Halo radius, age, spherical equivalent (SE), axial length (AL), initial diameter, amplitude of contraction, latency of contraction, duration of contraction, velocity of contraction, latency of dilation, duration of dilation, velocity of dilation, maximum pupil, minimum pupil, average pupil and dark pupil.

RESULTS

Significant associations were found between disk halo size and SE (r=-0.219, P=0.002), AL (r=0.152, P=0.033) and minimum pupil (r=0.149, P=0.037). There were no associations between disk halo size and initial diameter, amplitude of contraction, latency of contraction, duration of contraction, velocity of contraction, latency of dilation, duration of dilation, velocity of dilation, maximum pupil, average pupil, dark pupil and age (P>0.05). A significant difference in disk halo size was detected between the low-moderate and high myopia (SE< -6 D) groups (P=0.002) and between the small and large (minimum pupil≥4 mm) minimum pupil size groups (P=0.014).

CONCLUSIONS

Patients with a high SE and large minimum pupil size (minimum pupil ≥4 mm) suffered more disability glare than those with a low SE and small minimum pupil size.

摘要

目的

评估瞳孔对光反应、近视与视盘光晕大小之间的关系。

设计

横断面研究。

地点

单一屈光手术中心。

参与者

本研究对197例年龄在20至35岁之间患者的197只右眼进行了评估,使用视力监测仪测量视盘光晕大小和瞳孔对光反应。

主要和次要观察指标

光晕半径、年龄、等效球镜度(SE)、眼轴长度(AL)、初始直径、收缩幅度、收缩潜伏期、收缩持续时间、收缩速度、扩张潜伏期、扩张持续时间、扩张速度、最大瞳孔、最小瞳孔、平均瞳孔和暗瞳孔。

结果

发现视盘光晕大小与SE(r = -0.219,P = 0.002)、AL(r = 0.152,P = 0.033)和最小瞳孔(r = 0.149,P = 0.037)之间存在显著相关性。视盘光晕大小与初始直径、收缩幅度、收缩潜伏期、收缩持续时间、收缩速度、扩张潜伏期、扩张持续时间、扩张速度、最大瞳孔、平均瞳孔、暗瞳孔和年龄之间无相关性(P>0.05)。在低度至中度近视(SE < -6 D)组与高度近视组之间(P = 0.002)以及小瞳孔组与大瞳孔组(最小瞳孔≥4 mm)之间(P = 0.014),视盘光晕大小存在显著差异。

结论

等效球镜度高且最小瞳孔大(最小瞳孔≥4 mm)的患者比等效球镜度低且最小瞳孔小的患者遭受更多的失能眩光。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba55/5898290/6592fac7df10/bmjopen-2017-019914f01.jpg

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