Abuhamda Allam Fayez, Elsous Aymen, Al-Saadi Nasser, Al-Dadah Maher
Consultant Neonatologist, Shifa Hospital, NICU Department, Gaza Strip, Palestine.
Faculty of Health Professions, Israa University, Gaza Strip, Palestine.
Respir Med Case Rep. 2019 Sep 27;28:100937. doi: 10.1016/j.rmcr.2019.100937. eCollection 2019.
Congenital chylothorax (CCT) is a rare condition which is characterized by an accumulation of lymphatic fluid in the pleural space and exposes the newborn to respiratory distress and losing of proteins, coagulation factors and immunoglobulins. These cases are liable to have sepsis and high mortality rate. We report a case of a female fetus in Gaza delivered at 36 weeks gestational age diagnosed with CCT. The antenatal ultrasonography showed right sided significant pleural effusion and at birth; she had severe respiratory distress. The baby was intubated at birth and right-sided chest tube drain inserted to drain the pleural fluid which was chylus. The case responded partially to intravenous (IV) octreotide and sildenafil. Chylus stopped completely after 2 days of treatment with octreotide and medium chains triglyceride (MCT) oil-based formula feeding. : A female newborn diagnosed with right-sided pleural effusion by antenatal scan was confirmed to have congenital chylothorax postnataly. The infant responded to IV octreotide and MCT based formula feeding.
先天性乳糜胸（CCT）是一种罕见疾病，其特征为胸腔内积聚淋巴液，可导致新生儿出现呼吸窘迫，并造成蛋白质、凝血因子和免疫球蛋白流失。这些病例易发生败血症，死亡率高。我们报告一例加沙地区的女性胎儿，孕36周出生，诊断为先天性乳糜胸。产前超声检查显示右侧有大量胸腔积液，出生时她出现严重呼吸窘迫。婴儿出生时即行气管插管，并插入右侧胸腔引流管以引流乳糜样胸腔积液。该病例对静脉注射奥曲肽和西地那非有部分反应。使用奥曲肽治疗2天后，乳糜液完全停止，同时给予中链甘油三酯（MCT）油基配方奶喂养。：一名通过产前扫描诊断为右侧胸腔积液的女婴，出生后确诊为先天性乳糜胸。该婴儿对静脉注射奥曲肽和基于MCT的配方奶喂养有反应。
