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分泌性中耳炎患儿变应性鼻炎的患病率。

Prevalence of allergic rhinitis in children with otitis media with effusion.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Canselor Tuanku Mukhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

出版信息

Eur Ann Allergy Clin Immunol. 2020 May;52(3):121-130. doi: 10.23822/EurAnnACI.1764-1489.119. Epub 2020 May 5.

Abstract

The prevalence of allergic rhinitis in children with persistent otitis media with effusion in different countries varies between 82% to 93%. Many risk factors of otitis media with effusion has been studied and proven. However, its association with allergic rhinitis remains controversial. Objective. The main objective of this study is to determine the prevalence of allergic rhinitis in children with persistent otitis media with effusion. This study is also aimed to identify the risk factors of otitis media with effusion, common allergens associated with allergic rhinitis and determine the hearing threshold of children with otitis media with effusion. A hundred and thirty children were recruited. History taking, physical examination and hearing assessment were done in the first visit. Those with allergic rhinitis underwent skin prick test and treated with intranasal corticosteroid and antihistamine. A second examination and hearing assessment were then repeated after 3 months. The prevalence of allergic rhinitis in children with persistent otitis media with effusion in this study was noted to be 80.3%. Among these children, dust mites appeared to be the most common allergen (87.7%). Another risk factor appeared to be families with more than 4 members per-household (96%). It is noted that that otitis media with effusion caused a hearing loss up to 33 dB. However, there was a statistically significant improvement of the hearing threshold during second visit after commencement of allergy treatment. It was also noted that the hearing threshold in allergic rhinitis group was significantly impaired compared to the non-allergic rhinitis group. Allergic rhinitis and larger family household appeared to be common risk factors in children with persistent otitis media with effusion. There is significant hearing loss noted in children suffering from otitis media with effusion and allergic rhinitis. The hearing threshold improved remarkably with medical therapy. This study hence clarifies the controversy on the association between allergic rhinitis and otitis media with effusion.

摘要

在不同国家,持续性分泌性中耳炎儿童的变应性鼻炎患病率在 82%至 93%之间不等。许多分泌性中耳炎的危险因素已被研究并证实。然而,其与变应性鼻炎的相关性仍存在争议。目的:本研究旨在确定持续性分泌性中耳炎儿童的变应性鼻炎患病率。本研究还旨在确定分泌性中耳炎的危险因素、与变应性鼻炎相关的常见过敏原,并确定分泌性中耳炎儿童的听力阈值。共招募了 130 名儿童。在初次就诊时进行病史采集、体格检查和听力评估。有变应性鼻炎的儿童进行皮肤点刺试验,并接受鼻内皮质类固醇和抗组胺药物治疗。然后在 3 个月后重复进行第二次检查和听力评估。本研究中,持续性分泌性中耳炎儿童的变应性鼻炎患病率为 80.3%。在这些儿童中,尘螨似乎是最常见的过敏原(87.7%)。另一个危险因素似乎是每个家庭有 4 个以上成员的家庭(96%)。值得注意的是,分泌性中耳炎导致听力损失高达 33dB。然而,在开始过敏治疗后的第二次就诊时,听力阈值有统计学意义上的显著改善。还注意到,变应性鼻炎组的听力阈值明显比非变应性鼻炎组受损。变应性鼻炎和较大的家庭住户似乎是持续性分泌性中耳炎儿童的常见危险因素。患有分泌性中耳炎和变应性鼻炎的儿童有明显的听力损失。听力阈值在药物治疗后显著改善。本研究因此澄清了变应性鼻炎和分泌性中耳炎之间关联的争议。

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