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中耳积液与另一种环境相关疾病(特定过敏性疾病)的共现情况。

Co-occurrence of otitis media with effusion and another environment-dependent disease (selected allergic conditions).

作者信息

Wojas Oksana, Krzych-Fałta Edyta, Furmańczyk Konrad, Dziewa-Dawidczyk Diana, Samoliński Bolesław, Samel-Kowalik Piotr

机构信息

Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland.

Department Basic of Nursing, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland.

出版信息

Postepy Dermatol Alergol. 2024 Feb;41(1):78-84. doi: 10.5114/ada.2023.135602. Epub 2024 Feb 28.

Abstract

INTRODUCTION

Otitis media eith effusion (OME) is an inflammatory condition of the middle ear that involves accumulation of sterile fluid or effusion in the tympanic cavity with the tympanic membrane intact. The pathophysiology of OME is undoubtedly multifactorial.

AIM

To assess the co-occurrence of OME, allergic rhinitis, and asthma.

MATERIAL AND METHODS

The study involved a group of 18,617 subjects aged 6-7 years, 13-14 years, or 20-44 years. ECRHS and ISAAC questionnaires, validated and adopted for Polish conditions, were used in the study.

RESULTS

OME increases the risk of developing allergic rhinitis by nearly two-fold (OR = 2.07, 95% CI: 1.738-2.479 in 6-7-year-olds; OR = 1.61, 95% CI: 1.299-1.995 in 13-14-year-olds, and OR = 1.55, 95% CI: 1.262-1.83 in 20-44-year-olds). Protective factors against otitis media with effusion include the number of siblings (the more children in the family, the higher the risk of chronic OM; OR = 2.00, 95% CI: 1.15-1.346) and consumption of dairy products rich in lactic acid bacteria.

CONCLUSIONS

OME significantly more often co-exists with other conditions, particularly allergic rhinitis.

摘要

引言

中耳积液(OME)是一种中耳的炎症性疾病,其特征是在鼓膜完整的情况下,鼓室内积聚无菌液体或渗出液。OME的病理生理学无疑是多因素的。

目的

评估OME、过敏性鼻炎和哮喘的共病情况。

材料与方法

该研究纳入了一组年龄在6 - 7岁、13 - 14岁或20 - 44岁的18617名受试者。研究使用了针对波兰情况进行验证和采用的欧洲社区呼吸健康调查(ECRHS)问卷和国际儿童哮喘及过敏研究(ISAAC)问卷。

结果

OME使患过敏性鼻炎的风险增加近两倍(6 - 7岁儿童中,OR = 2.07,95%CI:1.738 - 2.479;13 - 14岁儿童中,OR = 1.61,95%CI:1.299 - 1.995;20 - 44岁人群中,OR = 1.55,95%CI:1.262 - 1.83)。预防中耳积液的保护因素包括兄弟姐妹的数量(家庭中孩子越多,患慢性中耳炎的风险越高;OR = 2.00,95%CI:1.15 - 1.346)以及食用富含乳酸菌的乳制品。

结论

OME与其他疾病,尤其是过敏性鼻炎,同时存在的情况更为常见。

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