Waldum H L, Burhol P G, Straume B K
Scand J Gastroenterol. 1978;13(8):943-6. doi: 10.3109/00365527809181373.
A conventional pentagastrin test was carried out in 25 patients with dyspeptic complaints, and gastric H+ and pepsin outputs were determined. Blood was drawn before the intubation and 5 and 30 min after subcutaneous injection of pentagastrin, and serum group I pepsinogens (PG I) and serum gastrin were determined by radioimmunoassay methods. A significant correlation was found between serum PG I, on the one hand, and basal gastric pepsin, output as well as pentagastrin-stimulated gastric H+ and pepsin outputs, on the other. Basal serum gastrin was also significantly correlated to pentagastrin-stimulated gastric pepsin output as well as to serum PG I. Pentagastrin failed to induce an increase in serum PG I during the first 30 min.
对25例有消化不良症状的患者进行了传统的五肽胃泌素试验，并测定了胃氢离子和胃蛋白酶分泌量。在插管前以及皮下注射五肽胃泌素后5分钟和30分钟采集血液，采用放射免疫分析法测定血清I组胃蛋白酶原（PG I）和血清胃泌素。一方面发现血清PG I与基础胃蛋白酶分泌量以及五肽胃泌素刺激后的胃氢离子和胃蛋白酶分泌量之间存在显著相关性。基础血清胃泌素也与五肽胃泌素刺激后的胃蛋白酶分泌量以及血清PG I显著相关。在最初30分钟内，五肽胃泌素未能使血清PG I升高。
