Respiratory Center, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China (mainland).
China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Engineering Research Center of Stem Cell Therapy, Chongqing, China (mainland).
Med Sci Monit. 2019 Nov 2;25:8221-8229. doi: 10.12659/MSM.915481.
BACKGROUND The prevalence of food allergies in asthmatic children and adolescents has significantly increased over recent years. Nevertheless, the relevant clinical analyses are still lacking in China. Therefore, the present study aimed to determine common food allergens in pediatric patients with asthma in Chongqing, Southwest China. MATERIAL AND METHODS A total of 8393 asthmatic patients from Children's Hospital of Chongqing Medical University (CHCMU) were enrolled in this retrospective study between October 2014 and July 2017. All patients underwent skin prick test (SPT) with 10 food allergens and recorded history of clinical reactivity. The correlations among the positive rates, categories of allergens, gender, age, and living environment were analyzed. RESULTS A total of 2544 patients (30.31%) had a positive SPT, while the prevalence of food allergy was 8%. Sea crab, peanut, and sea shrimp were the most common food allergens found in the studied population. The frequent food allergies were sea crab, peanuts, and sea shrimp. CONCLUSIONS Identifying allergens is important for the diagnosis and management of allergic disorders, and for performing immunotherapy.
近年来，哮喘患儿和青少年的食物过敏患病率显著增加。然而，中国仍缺乏相关的临床分析。因此，本研究旨在确定中国重庆地区哮喘患儿常见的食物过敏原。
本回顾性研究纳入了 2014 年 10 月至 2017 年 7 月在重庆医科大学儿童医院（CHCMU）就诊的 8393 例哮喘患者。所有患者均接受了 10 种食物过敏原的皮肤点刺试验（SPT），并记录了临床过敏反应史。分析了阳性率、过敏原类别、性别、年龄和生活环境之间的相关性。
共有 2544 例患者（30.31%）SPT 阳性，食物过敏的患病率为 8%。海蟹、花生和海虾是研究人群中最常见的食物过敏原。常见的食物过敏原有海蟹、花生和海虾。
确定过敏原对过敏症的诊断和管理以及免疫治疗非常重要。
