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水凝胶基商业产品在生物医学中的应用:综述。

Hydrogel-based commercial products for biomedical applications: A review.

机构信息

Department of Industrial Engineering, University of Salerno, 84084 Fisciano, SA, Italy.

Department of Industrial Engineering, University of Salerno, 84084 Fisciano, SA, Italy.

出版信息

Int J Pharm. 2020 Jan 5;573:118803. doi: 10.1016/j.ijpharm.2019.118803. Epub 2019 Nov 1.

Abstract

Hydrogels are hydrophilic polymer networks, able to absorb large amount of water, increasing their volume and showing a plethora of different material behaviors. Since their first practical application, dating from sixties of last century, they have been employed in several fields of biomedical sciences. After more than half a century of industrial uses, nowadays a lot of hydrogels are currently on the market for different purposes, and offering a wide spectra of features. In this review, even if it is virtually impossible to list all the commercial products based on hydrogels for biomedical applications, an extensive analysis of those materials that have reached the market has been carried out. The hydrogel-based materials used for drug delivery, wound dressing, tissue engineering, the building of contact lens, and hygiene products are enlisted and briefly described. A detailed snapshot of the set of these products that have reached the commercial maturity has been then obtained and presented. For each class of application, the basics of requirements are described, and then the materials are listed and classified on the basis of their chemical nature. For each product the commercial name, the producer, the chemical nature and the main characteristics are reported.

摘要

水凝胶是亲水性聚合物网络,能够吸收大量的水,增加其体积,并表现出多种不同的材料行为。自上世纪六十年代首次实际应用以来,它们已被应用于生物医学科学的多个领域。经过半个多世纪的工业用途,如今有许多水凝胶目前用于不同的目的,并提供广泛的特性。在这篇综述中,即使不可能列出所有基于水凝胶的用于生物医学应用的商业产品,也对已经进入市场的这些材料进行了广泛的分析。列出并简要描述了用于药物输送、伤口敷料、组织工程、隐形眼镜制造和卫生用品的基于水凝胶的材料。然后获得并呈现了已经达到商业成熟度的这组产品的详细快照。对于每种应用类别,都描述了基本要求,然后根据其化学性质对材料进行了列出和分类。对于每个产品,报告了商业名称、生产者、化学性质和主要特性。

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