Clinic of Urology, Clinical Centre of Serbia, 11060 Belgrade, Serbia.
Faculty of Medicine, University of Belgrade; Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Molecules. 2019 Nov 4;24(21):3982. doi: 10.3390/molecules24213982.
In recent years, the progress of science and medicine greatly has influenced human life span and health. However, lifestyle habits, like physical activity, smoking cessation, moderate alcohol consumption, diet, and maintaining a normal body weight represent measures that greatly reduce the risk of various diseases. The type of diet is very important for disease development. Numerous epidemiological clinical data confirm that longevity is linked to predominantly plant-based diets and it is related to a long life; whereas the western diet, rich in red meat and fats, increases the risk of oxidative stress and thus the risk of developing various diseases and pre-aging. This review is focused on the bioavailability of polyphenols and the use of polyphenols for the prevention of prostate diseases. Special focus in this paper is placed on the isoflavonoids and flavan-3-ols, subgroups of polyphenols, and their protective effects against the development of prostate diseases.
近年来，科学和医学的进步极大地影响了人类的寿命和健康。然而，生活方式习惯，如体育活动、戒烟、适量饮酒、饮食和保持正常体重，是大大降低各种疾病风险的措施。饮食类型对疾病的发展非常重要。大量的流行病学临床数据证实，长寿与以植物为主的饮食有关，与长寿有关；而富含红肉类和脂肪的西方饮食会增加氧化应激的风险，从而增加患各种疾病和早衰的风险。本文重点讨论了多酚的生物利用度以及多酚在预防前列腺疾病中的应用。本文特别关注多酚的亚类——异黄酮和黄烷-3-醇及其对预防前列腺疾病的保护作用。
