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临床上酷似横纹肌肉瘤的眼眶蜂窝织炎。

Orbital cellulitis clinically mimicking rhabdomyosarcoma.

作者信息

Amir Suliati P, Kamaruddin Muhammad Irfan, Akib Marliyanti Nur Rahmah, Sirajuddin Junaedi

机构信息

Department of Ophthalmology, Hasanuddin University, Makassar, South Sulawesi, Indonesia.

Department of Ophthalmology, Muslim University of Indonesia, Makassar, South Sulawesi, Indonesia.

出版信息

Int Med Case Rep J. 2019 Aug 26;12:285-289. doi: 10.2147/IMCRJ.S201678. eCollection 2019.

Abstract

INTRODUCTION

Proptosis in children with acute-onset accompanied by signs of inflammation is commonly caused by orbital cellulitis, however, the possibility of rhabdomyosarcoma should always be considered by the clinician. This is a case report of a five-year-old boy presenting with an acute-onset of proptosis without a history of trauma and systemic infection. Our clinical differential diagnosis included orbital cellulitis and orbital rhabdomyosarcoma.

PURPOSE

To report a case of orbital cellulitis that clinically and radiologically mimics rhabdomyosarcoma.

CASE PRESENTATION

A five-year-old boy presented with rapid-onset proptosis, periorbital edema, pain and visual loss in the left eye for two weeks without a history of trauma, upper respiratory tract infection, sinusitis or immunosuppression. Our clinical differential diagnosis includes rhabdomyosarcoma and orbital cellulitis. Complete blood count reveals a leukocytosis. Multislice computed tomography (MSCT) scan shows lesions involving the lateral orbit and the retro bulbar space. Antibiotics combination and adjunct anti-inflammatory intravenously shows excellent clinical resolution.

CONCLUSIONS

The study demonstrates difficulty in differentiating acute orbital cellulitis from rhabdomyosarcoma based on clinical findings. In addition, the case highlights that antibiotic combination of cephalosporin and aminoglycosides together with an adjuvant corticosteroid as an anti-inflammatory was effective in the case of acute orbital cellulitis.

摘要

引言

急性起病且伴有炎症体征的儿童突眼症通常由眼眶蜂窝织炎引起,然而,临床医生应始终考虑横纹肌肉瘤的可能性。本文报告一例5岁男孩,急性起病出现突眼症,无外伤及全身感染病史。我们的临床鉴别诊断包括眼眶蜂窝织炎和眼眶横纹肌肉瘤。

目的

报告一例临床上和影像学上酷似横纹肌肉瘤的眼眶蜂窝织炎病例。

病例介绍

一名5岁男孩,左眼迅速出现突眼、眶周水肿、疼痛及视力丧失2周,无外伤、上呼吸道感染、鼻窦炎或免疫抑制病史。我们的临床鉴别诊断包括横纹肌肉瘤和眼眶蜂窝织炎。血常规显示白细胞增多。多层计算机断层扫描(MSCT)显示病变累及眼眶外侧及球后间隙。联合使用抗生素及辅助性静脉抗炎治疗后临床症状显著缓解。

结论

该研究表明,基于临床表现难以区分急性眼眶蜂窝织炎和横纹肌肉瘤。此外,该病例突出显示,头孢菌素和氨基糖苷类抗生素联合辅助性皮质类固醇作为抗炎药物对急性眼眶蜂窝织炎有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c561/6716584/0398c56a5cbc/IMCRJ-12-285-g0001.jpg

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