Soorani-Lunsing R J, Hadders-Algra M, Olinga A A, Huisjes H J, Touwen B C
Department of Developmental Neurology, University Hospital Groningen, The Netherlands.
Dev Med Child Neurol. 1993 Apr;35(4):321-30. doi: 10.1111/j.1469-8749.1993.tb11644.x.
Behavioural and cognitive development at 12 years were studied in 172 children with and 174 children without minor neurological dysfunction (MND). MND could be differentiated into fine manipulative disability, co-ordination problems, hypotonia and choreiform dyskinesia. Fine manipulative disability related significantly to problems of cognition and behaviour; co-ordination problems to cognitive problems; and hypotonia and choreiform dyskinesia to behavioural problems, the former more than the latter. Socio-economic status and family adversity contributed to the risk for development of both cognitive and behavioural problems; gender did not. The onset of puberty seemed to change these relationships: follow-up is needed for definite conclusions.