Graduate School of Dalian Medical University, Dalian, China.
Department of Urinary Surgery, PLA 967th Hospital, Dalian, China.
Sci Rep. 2019 Nov 7;9(1):16264. doi: 10.1038/s41598-019-52680-x.
The purpose of this study was to investigate the relationship between isovolumic relaxation flow (IRF) patterns in left ventricle (LV) and mitral inflow patterns. Color Doppler loops were acquired for vector flow mapping in apical long-axis view in 57 patients with coronary artery disease, 31 patients with dilated cardiomyopathy, and 58 healthy controls. IRF patterns were classified into three categories: pattern A, apically directed flow; pattern B, bidirectional flow with small scattered vortices; and pattern C, a large vortex. All normals and patients with normal LV filling (n = 10) showed pattern A. Patients with impaired relaxation consisted of 31 (66%) patients having pattern A, 11 (23%) having pattern B, and 5 (11%) having pattern C. Patients with pseudonormal filling included 4 (31%) patients having pattern A, 7 (54%) having pattern B, and 2 (15%) having pattern C. In patients with restrictive filling, 14 (78%) showed pattern C, 4 (22%) showed pattern B, and no patient showed pattern A. IRF patterns were associated with LV filling patterns (χ = 52.026, p < 0.001). There are significant relationships between LV filling and IRF patterns. IRF patterns may provide an index for evaluation of LV diastolic function.
本研究旨在探讨左心室（LV）等容舒张流（IRF）模式与二尖瓣血流模式之间的关系。在 57 例冠心病患者、31 例扩张型心肌病患者和 58 例健康对照者的心尖长轴切面获得彩色多普勒环用于向量血流图。将 IRF 模式分为 3 类：A 型，心尖指向的血流；B 型，小散在涡流的双向血流；和 C 型，大涡流。所有正常人和 LV 充盈正常的患者（n=10）均表现为 A 型。松弛功能障碍患者中，31 例（66%）为 A 型，11 例（23%）为 B 型，5 例（11%）为 C 型。假性正常充盈患者中，4 例（31%）为 A 型，7 例（54%）为 B 型，2 例（15%）为 C 型。在限制性充盈患者中，14 例（78%）为 C 型，4 例（22%）为 B 型，无患者为 A 型。IRF 模式与 LV 充盈模式相关（χ²=52.026，p<0.001）。LV 充盈与 IRF 模式之间存在显著关系。IRF 模式可能为评估 LV 舒张功能提供一个指标。
