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维生素 D 与女性抑郁症:小型综述

Vitamin D and Depression in Women: A Mini-review.

机构信息

International Research Centre "Biotechnologies of the Third Millennium", ITMO University, 9 Lomonosova Str. St. Petersburg 191002, Russian Federation.

Laboratory of Neuroendocrinology, I.P. Pavlov Institute of Physiology RASci., 6 Emb. Makarova, St. Petersburg 199034, Russian Federation.

出版信息

Curr Neuropharmacol. 2020;18(4):288-300. doi: 10.2174/1570159X17666191108111120.

Abstract

Affective-related disorders, including depression, are constantly rising, complicating people's personal lifestyle increasing disqualification and hospital care. Because of the high intensity of urbanization, our lifestyle and food have altered dramatically in the last twenty years. These food modifications have been associated with scores of depression and other affective-related disorders in urbanized countries with high economic levels. Nutrients imbalance is considered as one of the critical causes enabling the pathophysiological mechanisms for the development of psychiatric disorders. The application of additional nutritional interventions for treatment of mood deteriorations can be beneficial for both the prophylaxis and therapy of affective-related disorders. This paper will review recent research on the relation of Vitamin D levels and the epidemiology of depression in women. In this paper, we will provide an overview of the results of a variety of different studies taking into account research which both suggests and refutes an association. Based on these findings we will propose important directions for future research in relation to this topic.

摘要

情感相关障碍,包括抑郁症,不断上升,使人们的个人生活方式变得复杂,增加了不合格和住院治疗的几率。由于城市化程度的提高,过去二十年来,我们的生活方式和饮食发生了巨大变化。这些饮食的改变与城市化程度高、经济水平高的国家中大量的抑郁症和其他情感相关障碍有关。营养失衡被认为是使精神障碍发展的病理生理机制发生的关键原因之一。额外的营养干预措施的应用对于情绪恶化的治疗可能对情感相关障碍的预防和治疗都有益。本文将综述维生素 D 水平与女性抑郁症的流行病学关系的最新研究。在本文中,我们将概述各种不同研究的结果,同时考虑到既表明又反驳关联的研究。基于这些发现,我们将为这一主题的未来研究提出重要方向。

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