Yoshida K, Ichiman Y, Umeda A, Takeuchi S
Department of Microbiology, St Marianna University School of Medicine, Kawasaki, Japan.
J Appl Bacteriol. 1988 Jun;64(6):483-6. doi: 10.1111/j.1365-2672.1988.tb02439.x.
A compact type variant designated as strain ST67V was isolated by a high-temperature subculture method from strain ST67P of Staphylococcus hyicus, which was a diffuse type in serum-soft agar. The parent strain was relatively virulent in mice and resisted ingestion by mouse peritoneal cells. The variant strain, however, was avirulent in mice and no antiphagocytic activity was observed in the peritoneal cavity. In ultra-thin sections of the organisms treated with anti-ST67P rabbit anti-serum conjugated with ferritin, the outermost layer of the cell wall of the parent strain was covered with a well-defined capsule while no capsule was shown in the variant strain.
通过高温传代培养法从猪葡萄球菌ST67P菌株（血清软琼脂中的扩散型菌株）中分离出一种紧凑型变体，命名为ST67V菌株。亲本菌株对小鼠具有较高的毒力，且能抵抗小鼠腹腔细胞的吞噬作用。然而，变体菌株对小鼠无毒力，且在腹腔中未观察到抗吞噬活性。在用与铁蛋白偶联的抗ST67P兔抗血清处理的生物体超薄切片中，亲本菌株细胞壁的最外层覆盖有一层清晰的荚膜，而变体菌株中未显示有荚膜。
