Gautret Philippe, Angelo Kristina M, Asgeirsson Hilmir, Duvignaud Alexandre, van Genderen Perry J J, Bottieau Emmanuel, Chen Lin H, Parker Salim, Connor Bradley A, Barnett Elizabeth D, Libman Michael, Hamer Davidson H
Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France and IHU-Méditerranée Infection, Marseille, France.
Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, GA, USA.
Travel Med Infect Dis. 2019 November/December;32:101504. doi: 10.1016/j.tmaid.2019.101504. Epub 2019 Nov 9.
Travelers to international mass gatherings may be exposed to conditions which increase their risk of acquiring infectious diseases. Most existing data come from single clinical sites seeing returning travelers, or relate to single events.
Investigators evaluated ill travelers returning from a mass gathering, and presenting to a GeoSentinel site between August 2015 and April 2019, and collected data on the nature of the event and the relation between final diagnoses and the mass gathering.
Of 296 ill travelers, 51% were female and the median age was 54 years (range: 1-88). Over 82% returned from a religious mass gathering, most frequently Umrah or Hajj. Only 3% returned from the Olympics in Brazil or South Korea. Other mass gatherings included other sporting events, cultural or entertainment events, and conferences. Respiratory diseases accounted for almost 80% of all diagnoses, with vaccine preventable illnesses such as influenza and pneumonia accounting for 26% and 20% of all diagnoses respectively. This was followed by gastrointestinal illnesses, accounting for 4.5%. Sixty-three percent of travelers reported having a pre-travel encounter with a healthcare provider.
Despite this surveillance being limited to patients presenting to GeoSentinel sites, our findings highlight the importance of respiratory diseases at mass gatherings, the need for pre-travel consultations before mass gatherings, and consideration of vaccination against influenza and pneumococcal disease.
前往国际大型集会的旅行者可能会面临增加感染传染病风险的情况。现有的大多数数据来自接待归国旅行者的单一临床地点，或与单一事件相关。
研究人员评估了2015年8月至2019年4月期间从大型集会返回并前往地理哨兵监测点就诊的患病旅行者，并收集了有关活动性质以及最终诊断与大型集会之间关系的数据。
在296名患病旅行者中，51%为女性，年龄中位数为54岁（范围：1 - 88岁）。超过82%的人从宗教大型集会返回，最常见的是小朝觐或大朝觐。只有3%的人从巴西或韩国的奥运会返回。其他大型集会包括其他体育赛事、文化或娱乐活动以及会议。呼吸系统疾病占所有诊断病例的近80%，其中流感和肺炎等可通过疫苗预防的疾病分别占所有诊断病例的26%和20%。其次是胃肠道疾病，占4.5%。63%的旅行者报告在旅行前曾与医疗服务提供者接触。
尽管这项监测仅限于前往地理哨兵监测点就诊的患者，但我们的研究结果突出了大型集会中呼吸系统疾病的重要性、大型集会前进行旅行前咨询的必要性以及考虑接种流感和肺炎球菌疾病疫苗。
