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烟草消费对有隐睾病史成年人的生育力的影响。

The effects of tobacco consumption on paternity rates of adults with a history of cryptorchidism.

作者信息

Fernández Atuan Rafael, Calleja Aguayo Elena, Estors Sastre Blanca, Álvarez García Natalia, Siles Hinojosa Alexander, Bragagnini Rodríguez Paolo, Gracia Romero Jesus

机构信息

Hospital Universitario Miguel Servet, Zaragoza, Spain.

Hospital Universitari Son Espases, Palma, Spain.

出版信息

Pediatr Surg Int. 2020 Feb;36(2):241-246. doi: 10.1007/s00383-019-04598-8. Epub 2019 Nov 11.

DOI:10.1007/s00383-019-04598-8
PMID:31712873
Abstract

OBJECTIVE

To determine the effect of tobacco consumption on paternity rates in men with a history of cryptorchidism. To compare the paternity rates between formerly unilateral, bilateral cryptorchid smokers, and nonsmokers.

METHODS

A retrospective cohort study of 153 men who had undergone orchiopexy between 1961 and 1985 at the Miguel Servet University Hospital (116 unilateral and 37 bilateral) and a control group of 100 men were evaluated by review of medical records and a questionnaire.

RESULTS

A total of 197 men filled the questionnaire (76.7%). There was no difference in paternity rates between smokers compared to nonsmokers (P = 0.21). In the unilateral cryptorchid men (ULC) group, there is no difference in paternity rates when compared with the controls (P = 0.079) or when comparing ULC smokers to ULC nonsmokers (P = 0.35). In the bilateral cryptorchid men (BLC) group, there is no difference in paternity rates when compared to controls (P = 0.075) or when comparing BLC smokers to BLC nonsmokers (P = 0.36). When comparing according to consumption, there is no difference between mild, moderate or heavy smoker cases and controls.

CONCLUSION

There is no difference in paternity rates between men with a history of cryptorchidism that consume tobacco compared to nonsmokers or controls. More studies are needed to determine the impact of tobacco consumption in formerly cryptorchid men.

摘要

目的

确定吸烟对有隐睾病史男性的生育力的影响。比较既往单侧、双侧隐睾的吸烟者与非吸烟者之间的生育力。

方法

对1961年至1985年间在米格尔·塞尔维特大学医院接受睾丸固定术的153名男性(116名单侧和37名双侧)进行回顾性队列研究,并通过查阅病历和问卷调查对100名男性组成的对照组进行评估。

结果

共有197名男性填写了问卷(76.7%)。吸烟者与非吸烟者的生育力无差异(P = 0.21)。在单侧隐睾男性(ULC)组中,与对照组相比生育力无差异(P = 0.079),或比较ULC吸烟者与ULC非吸烟者时也无差异(P = 0.35)。在双侧隐睾男性(BLC)组中,与对照组相比生育力无差异(P = 0.075),或比较BLC吸烟者与BLC非吸烟者时也无差异(P = 0.36)。根据吸烟量比较时,轻度、中度或重度吸烟者与对照组之间无差异。

结论

有隐睾病史的吸烟者与非吸烟者或对照组相比,生育力无差异。需要更多研究来确定吸烟对既往隐睾男性的影响。

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The effects of tobacco consumption on paternity rates of adults with a history of cryptorchidism.烟草消费对有隐睾病史成年人的生育力的影响。
Pediatr Surg Int. 2020 Feb;36(2):241-246. doi: 10.1007/s00383-019-04598-8. Epub 2019 Nov 11.
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