Abramovici H, Dirnfeld M, Weisman Z, Sorokin Y, Lissak A, Rofe A, Sheinfeld M
Department of Obstetrics and Gynecology, Carmel Medical Center, Haifa, Israel.
J In Vitro Fert Embryo Transf. 1988 Jun;5(3):175-6. doi: 10.1007/BF01131183.
In 16 women undergoing IVF-ET, with more than four embryos available, two transfers were performed (24 hr apart), instead of one. The pregnancy rate was 25%, as compared with a pregnancy rate of 6.2% in 16 women having fewer than four embryos available and in whom one conventional transfer was performed. Since in our IVF-ET program, we do not freeze the extra embryos available, the purpose of the double transfer was to use all the embryos available and to improve the chances of finding the "implantation window" open. It is our feeling that multiple transfers may be beneficial to improve the pregnancy rate in an IVF-ET program without freezing facilities. However, a larger controlled clinical trial is necessary, in order to establish the advantages of multiple transfers in terms of pregnancy rate in comparison with the potential disadvantages.
在16名接受体外受精-胚胎移植（IVF-ET）且有超过4个胚胎可用的女性中，进行了两次移植（间隔24小时），而非一次。其妊娠率为25%，相比之下，16名有少于4个可用胚胎且进行了一次传统移植的女性，妊娠率为6.2%。由于在我们的体外受精-胚胎移植项目中，我们不会冷冻多余的可用胚胎，进行两次移植的目的是利用所有可用胚胎，并提高找到“着床窗”开放的几率。我们认为，在没有冷冻设备的体外受精-胚胎移植项目中，多次移植可能有利于提高妊娠率。然而，有必要进行一项更大规模的对照临床试验，以确定多次移植在妊娠率方面相对于潜在劣势的优势。
