Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
1st Department of Otorhinolaryngology, University of Athens, Hippokration Hospital of Athens, Athens, Greece.
Curr Cardiol Rev. 2020;16(4):266-274. doi: 10.2174/1573403X15666191111123622.
The globalization of the Western lifestyle has resulted in increase of diabetes mellitus, a complex, multifactorial disease. Diabetes mellitus is a condition often related to the disorders of the cardiovascular system. It is well established that three quarters of diabetics, aged over 40, will die from cardiovascular disease and are more likely than non-diabetics to die from their first cardiovascular event. Therefore, it is of paramount importance to individualize treatment via risk stratification. Conditions that increase cardiovascular risk in people with diabetes include age more than 40 years, male gender, history of relative suffering from premature CHD, blood pressure and high LDL levels, presence of microalbuminuria, obstructive sleepapnea, erectile dysfunction and other conditions. Several models have been developed in order to assess cardiovascular risk in people with and without diabetes. Some of them have been proven to be inadequate while others are widely used for years. An emerging way of risk assessment in patients with diabetes mellitus is the use of biomarkers but a lot of research needs to be done in this field in order to have solid conclusions.
西方生活方式的全球化导致了糖尿病(一种复杂的、多因素的疾病)发病率的上升。糖尿病通常与心血管系统紊乱有关。众所周知,四分之三的 40 岁以上糖尿病患者将死于心血管疾病,并且他们死于首次心血管事件的可能性高于非糖尿病患者。因此,通过风险分层来个体化治疗至关重要。增加糖尿病患者心血管风险的因素包括年龄大于 40 岁、男性、有亲属早发冠心病病史、血压和 LDL 水平升高、存在微量白蛋白尿、阻塞性睡眠呼吸暂停、勃起功能障碍和其他情况。已经开发了几种模型来评估有和没有糖尿病的患者的心血管风险。其中一些已被证明是不充分的,而另一些则已被广泛使用多年。在糖尿病患者中,一种新的风险评估方法是使用生物标志物,但在该领域还需要进行大量研究,以便得出可靠的结论。