Newell D G, Hudson M J, Baskerville A
Experimental Pathology Laboratory, PHLS Centre for Applied Microbiology and Research, Salisbury.
J Med Microbiol. 1988 Sep;27(1):41-4. doi: 10.1099/00222615-27-1-41.
Campylobacter-like organisms, isolated from the gastric antrum of Rhesus monkeys, were compared with Campylobacter jejuni and C. pylori. They were similar to C. pylori by light microscopy, in ultrastructural morphology, in enzymic, fatty-acid-methyl-ester, and protein-profile analysis, and in antigenic reactivity with rabbit antisera to C. jejuni and C. pylori and with C. pylori-specific monoclonal antibody. Because this natural infection of the Rhesus monkey is associated with chronic gastritis, resembling the disease in humans colonised with C. pylori, we recommend the animal as a model for the investigation of human gastritis.
从恒河猴胃窦分离出的类弯曲杆菌属微生物，与空肠弯曲菌和幽门螺杆菌进行了比较。通过光学显微镜、超微结构形态学、酶学、脂肪酸甲酯和蛋白质谱分析，以及与针对空肠弯曲菌和幽门螺杆菌的兔抗血清及幽门螺杆菌特异性单克隆抗体的抗原反应性分析，发现它们与幽门螺杆菌相似。由于恒河猴的这种自然感染与慢性胃炎有关，类似于人类感染幽门螺杆菌后的疾病，我们建议将该动物作为研究人类胃炎的模型。
