M Selveindran Santhani, Khan Muhammad Mukhtar, Simadibrata Daniel Martin, Hutchinson Peter J A, Brayne Carol, Hill Christine, Kolias Angelos, Joannides Alexis J, Servadei Franco, Rubiano Andres M, Shabani Hamisi K
Institute of Public Health, University of Cambridge, Cambridge, Cambridgeshire, UK
NIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, Cambridgeshire, UK.
BMJ Open. 2019 Nov 12;9(11):e031517. doi: 10.1136/bmjopen-2019-031517.
Neurotrauma is an important global health problem. This 'silent epidemic' is a major cause of death and disability in adolescents and young adults, with significant societal and economic impacts. Globally, the largest cause of neurotrauma is road traffic collisions (RTCs). Neurotrauma and RTCs are largely preventable, and many preventative strategies and interventions have been established and implemented over the last decades, particularly in high-income countries. However, these approaches may not be applicable globally, due to variations in environment, resources, population, culture and infrastructure. This paper outlines the protocol for a scoping review, which seeks to map the evidence on strategies and interventions in neurotrauma and RTCs prevention globally, and to ascertain contextual factors that influence their implementation.
This scoping review will use the established methodology by Arksey and O'Malley. Eligible studies will be identified from five electronic databases (MEDLINE, EMBASE, CINAHL, Global Health/EBSCO and Cochrane Database of Systematic Reviews) and grey literature sources. We will also carry out bibliographical and citation searching of included studies. A two-stage selection process, which involves screening of titles and abstracts, followed by full-text screening, will be used to determine eligible studies which will undergo data abstraction using a customised, piloted data extraction sheet. The extracted data will be presented using evidence mapping and a narrative summary.
Ethical approval is not required for this scoping review, which is the first step in a multiphase public health research project on the global prevention of neurotrauma. The final review will be submitted for publication to a scientific journal, and results will be presented at appropriate conferences, workshops and meetings. Protocol registered on 5 April 2019 with Open Science Framework (https://osf.io/s4zk3/).
神经创伤是一个重要的全球性健康问题。这种“无声的流行病”是青少年和青年死亡及残疾的主要原因，具有重大的社会和经济影响。在全球范围内，神经创伤的最大原因是道路交通事故（RTC）。神经创伤和道路交通事故在很大程度上是可以预防的，在过去几十年里已经制定并实施了许多预防策略和干预措施，特别是在高收入国家。然而，由于环境、资源、人口、文化和基础设施的差异，这些方法可能不适用于全球。本文概述了一项范围综述的方案，该综述旨在梳理全球神经创伤和道路交通事故预防策略及干预措施的证据，并确定影响其实施的背景因素。
本范围综述将采用Arksey和O'Malley确立的方法。将从五个电子数据库（MEDLINE、EMBASE、CINAHL、Global Health/EBSCO和Cochrane系统评价数据库）以及灰色文献来源中识别符合条件的研究。我们还将对纳入研究进行文献目录和引文检索。将采用两阶段选择过程，先筛选标题和摘要，然后进行全文筛选，以确定符合条件的研究，这些研究将使用定制的、经过试点的数据提取表进行数据提取。提取的数据将通过证据映射和叙述性总结呈现。
本范围综述无需伦理批准，它是全球预防神经创伤多阶段公共卫生研究项目的第一步。最终综述将提交给科学期刊发表，研究结果将在适当的会议、研讨会和会议上展示。方案于2019年4月5日在开放科学框架（https://osf.io/s4zk3/）上注册。
