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本文引用的文献

1
A Novel Inducible Mouse Model of -driven Mixed-lineage Acute Leukemia.一种新型的由驱动的混合谱系急性白血病诱导小鼠模型。
Hemasphere. 2018 Jun 12;2(4):e51. doi: 10.1097/HS9.0000000000000051. eCollection 2018 Aug.
2
leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing.利用基因组编辑技术在人造血干细胞中诱导 t(9;11)染色体易位所致白血病。
Blood Adv. 2018 Apr 24;2(8):832-845. doi: 10.1182/bloodadvances.2017013748.
3
The AF4-MLL fusion transiently augments multilineage hematopoietic engraftment but is not sufficient to initiate leukemia in cord blood CD34 cells.AF4-MLL融合蛋白可短暂增强多谱系造血植入，但不足以在脐血CD34细胞中引发白血病。
Oncotarget. 2017 Jul 26;8(47):81936-81941. doi: 10.18632/oncotarget.19567. eCollection 2017 Oct 10.
4
Intratumoral heterogeneity and clonal evolution in blood malignancies and solid tumors.血液系统恶性肿瘤和实体瘤中的肿瘤内异质性与克隆进化。
Oncotarget. 2017 Aug 16;8(39):66742-66746. doi: 10.18632/oncotarget.20279. eCollection 2017 Sep 12.
5
Modeling mixed-lineage-rearranged leukemia initiation in CD34 cells: a "CRISPR" solution.模拟CD34细胞中混合谱系重排白血病的起始：一种“CRISPR”解决方案。
Haematologica. 2017 Sep;102(9):1467-1468. doi: 10.3324/haematol.2017.173740.
6
Molecular processes involved in B cell acute lymphoblastic leukaemia.B 细胞急性淋巴细胞白血病涉及的分子过程。
Cell Mol Life Sci. 2018 Feb;75(3):417-446. doi: 10.1007/s00018-017-2620-z. Epub 2017 Aug 17.
7
The MLL recombinome of acute leukemias in 2017.2017 年急性白血病的 MLL 重排组。
Leukemia. 2018 Feb;32(2):273-284. doi: 10.1038/leu.2017.213. Epub 2017 Jul 13.
8
CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells .CRISPR-Cas9 诱导的 t(11;19)/MLL-ENL 易位导致人类造血祖细胞白血病的发生。
Haematologica. 2017 Sep;102(9):1558-1566. doi: 10.3324/haematol.2017.164046. Epub 2017 Jun 1.
9
Mouse models of MLL leukemia: recapitulating the human disease.MLL白血病的小鼠模型：重现人类疾病
Blood. 2017 Apr 20;129(16):2217-2223. doi: 10.1182/blood-2016-10-691428. Epub 2017 Feb 8.
10
Mixed-phenotype acute leukemia: current challenges in diagnosis and therapy.混合表型急性白血病：诊断与治疗中的当前挑战
Curr Opin Hematol. 2017 Mar;24(2):139-145. doi: 10.1097/MOH.0000000000000322.

The "Never-Ending" Mouse Models for MLL-Rearranged Acute Leukemia Are Still Teaching Us.

作者信息

Ottersbach Katrin, Sanjuan-Pla Alejandra, Torres-Ruíz Raúl, Bueno Clara, Velasco-Hernández Talia, Menendez Pablo

机构信息

MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.

Hematology Research Group, IIS La Fe, Valencia, Spain.

出版信息

Hemasphere. 2018 Jun 19;2(4):e57. doi: 10.1097/HS9.0000000000000057. eCollection 2018 Aug.

DOI:10.1097/HS9.0000000000000057
PMID:31723783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6746004/
Abstract
摘要