Amiez Céline, Procyk Emmanuel
Univ Lyon, Université Lyon 1, Inserm, Stem Cell and Brain Research Institute U1208, Bron, France.
Handb Clin Neurol. 2019;166:53-71. doi: 10.1016/B978-0-444-64196-0.00004-2.
The midcingulate cortex (MCC) is viewed as a central node within a large-scale system devoted to adjusting behavior in the face of changing environments. Whereas the role of the MCC in interfacing action and cognition is well established, its role in regulating the autonomic nervous system is poorly understood. Yet, adaptive reactions to novel or threatening situations induce coordinated changes in the sympathetic and the parasympathetic systems. The somatomotor maps in the MCC are organized dorsoventrally. A meta-analysis of the literature reveals that the dorsoventral organization might also concern connections with the autonomic nervous system. Activation of the dorsal and ventral parts of the MCC correlate with recruitments of the sympathetic and the parasympathetic systems, respectively. Data also suggest that, in the MCC, projections toward the sympathetic system are mapped along the sensory-motor system following the same cervico-sacral organization as projections on the spinal cord for skeletal motor control.
扣带前皮质（MCC）被视为一个大规模系统的核心节点，该系统致力于在不断变化的环境中调整行为。虽然MCC在连接动作和认知方面的作用已得到充分确立，但其在调节自主神经系统方面的作用却知之甚少。然而，对新的或威胁性情况的适应性反应会引起交感神经系统和副交感神经系统的协调变化。MCC中的躯体运动图谱是背腹式组织的。对文献的荟萃分析表明，背腹组织可能也与自主神经系统的连接有关。MCC背侧和腹侧部分的激活分别与交感神经系统和副交感神经系统的激活相关。数据还表明，在MCC中，向交感神经系统的投射沿着感觉运动系统分布，其组织方式与脊髓上用于骨骼肌运动控制的投射相同，呈颈骶式分布。
