Sadaka Ama, Nguyen Kimberly, Malik Amina, Brito Rosbel, Berry Shauna, Lee Andrew G
Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, USA.
Houston Medical School, University of Texas Health Science Center, Houston, Texas, USA.
Neuroophthalmology. 2019 Jan 25;43(5):291-294. doi: 10.1080/01658107.2019.1566382. eCollection 2019 Nov.
There is growing evidence of thyroid eye disease association with nutritional deficiencies including selenium and vitamin D. We conducted a retrospective chart review of all patients with clinical diagnosis of TED seen at our clinic from 2016 to 2017. Thirty-five patients met inclusion criteria and had serum 25-hydroxyvitamin D levels available, and 19 had selenium levels available. 7/35 (20%) patients had vitamin D deficiency, and 11 (31%) had vitamin D insufficiency, but none had selenium deficiency. Although both selenium and vitamin D supplementation have been recommended for TED, further investigation is necessary to justify supplementation for patients with TED.
越来越多的证据表明,甲状腺眼病与包括硒和维生素D在内的营养缺乏有关。我们对2016年至2017年在我们诊所临床诊断为TED的所有患者进行了回顾性病历审查。35名患者符合纳入标准且有血清25-羟基维生素D水平数据,19名患者有硒水平数据。7/35(20%)的患者有维生素D缺乏,11名(31%)有维生素D不足,但无人有硒缺乏。尽管已建议对TED患者补充硒和维生素D,但仍需进一步研究以证明对TED患者进行补充的合理性。