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Simultaneous induction of Graves' hyperthyroidism and Graves' ophthalmopathy by TSHR genetic immunization in BALB/c mice.在BALB/c小鼠中通过促甲状腺素受体基因免疫同时诱导格雷夫斯甲状腺功能亢进症和格雷夫斯眼病。
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Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis.多种营养因素与桥本甲状腺炎风险
Thyroid. 2017 May;27(5):597-610. doi: 10.1089/thy.2016.0635. Epub 2017 Apr 6.
3
Selenium and Thyroid Disease: From Pathophysiology to Treatment.硒与甲状腺疾病:从病理生理学到治疗
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Association of vitamin D status and clinical and radiological outcomes in a treated MS population in Poland.波兰治疗后多发性硬化症人群的维生素 D 状况与临床和放射学结果的关联。
Brain Behav. 2016 Dec 7;7(2):e00609. doi: 10.1002/brb3.609. eCollection 2017 Feb.
5
Effect of Selenium Supplementation on Recurrent Hyperthyroidism Caused by Graves' Disease: A Prospective Pilot Study.补充硒对格雷夫斯病所致复发性甲状腺功能亢进症的影响:一项前瞻性试点研究。
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The chronic autoimmune thyroiditis quality of life selenium trial (CATALYST): study protocol for a randomized controlled trial.慢性自身免疫性甲状腺炎生活质量硒试验(CATALYST):一项随机对照试验的研究方案。
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Serum selenium status in Graves' disease with and without orbitopathy: a case-control study.伴有和不伴有眼眶病的格雷夫斯病患者的血清硒水平:一项病例对照研究。
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德克萨斯州甲状腺眼病患者群体中的维生素D和硒

Vitamin D and Selenium in a Thyroid Eye Disease Population in Texas.

作者信息

Sadaka Ama, Nguyen Kimberly, Malik Amina, Brito Rosbel, Berry Shauna, Lee Andrew G

机构信息

Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, USA.

Houston Medical School, University of Texas Health Science Center, Houston, Texas, USA.

出版信息

Neuroophthalmology. 2019 Jan 25;43(5):291-294. doi: 10.1080/01658107.2019.1566382. eCollection 2019 Nov.

DOI:10.1080/01658107.2019.1566382
PMID:31741672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6844498/
Abstract

There is growing evidence of thyroid eye disease association with nutritional deficiencies including selenium and vitamin D. We conducted a retrospective chart review of all patients with clinical diagnosis of TED seen at our clinic from 2016 to 2017. Thirty-five patients met inclusion criteria and had serum 25-hydroxyvitamin D levels available, and 19 had selenium levels available. 7/35 (20%) patients had vitamin D deficiency, and 11 (31%) had vitamin D insufficiency, but none had selenium deficiency. Although both selenium and vitamin D supplementation have been recommended for TED, further investigation is necessary to justify supplementation for patients with TED.

摘要

越来越多的证据表明,甲状腺眼病与包括硒和维生素D在内的营养缺乏有关。我们对2016年至2017年在我们诊所临床诊断为TED的所有患者进行了回顾性病历审查。35名患者符合纳入标准且有血清25-羟基维生素D水平数据,19名患者有硒水平数据。7/35(20%)的患者有维生素D缺乏,11名(31%)有维生素D不足,但无人有硒缺乏。尽管已建议对TED患者补充硒和维生素D,但仍需进一步研究以证明对TED患者进行补充的合理性。