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用蜱中肠的可溶性抗原和膜相关抗原对赫里福德牛进行免疫接种,使其对微小牛蜱产生抗性。

Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks.

作者信息

Opdebeeck J P, Wong J Y, Jackson L A, Dobson C

机构信息

Department of Parasitology, University of Queensland, St Lucia, Brisbane, Australia.

出版信息

Parasite Immunol. 1988 Jul;10(4):405-10. doi: 10.1111/j.1365-3024.1988.tb00230.x.

Abstract

Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination.

摘要

用微小牛蜱中肠提取的膜和可溶性成分对海福特牛进行免疫接种。膜疫苗能保护牛(91%)免受每隔7天接种3×20,000只幼虫蜱的攻击。由可溶性抗原制成的疫苗不能保护牛。通过酶联免疫吸附测定(ELISA)测量的抗体水平与疫苗接种诱导的保护水平相关。

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