Opdebeeck J P, Wong J Y, Jackson L A, Dobson C
Department of Parasitology, University of Queensland, St Lucia, Brisbane, Australia.
Parasite Immunol. 1988 Jul;10(4):405-10. doi: 10.1111/j.1365-3024.1988.tb00230.x.
Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination.
用微小牛蜱中肠提取的膜和可溶性成分对海福特牛进行免疫接种。膜疫苗能保护牛(91%)免受每隔7天接种3×20,000只幼虫蜱的攻击。由可溶性抗原制成的疫苗不能保护牛。通过酶联免疫吸附测定(ELISA)测量的抗体水平与疫苗接种诱导的保护水平相关。