Mania Szymon, Ryl Jacek, Jinn Jia-Rong, Wang Ya-Jane, Michałowska Anna, Tylingo Robert
Chemical Faculty, Department of Chemistry, Technology and Biotechnology of Food, Gdansk University of Technology, 11/12 G. Narutowicza Str., 80-233 Gdansk, Poland.
Chemical Faculty, Department of Electrochemistry, Corrosion and Material Engineering, Gdansk University of Technology, 11/12 G. Narutowicza Str., 80-233 Gdansk, Poland.
Polymers (Basel). 2019 Nov 16;11(11):1893. doi: 10.3390/polym11111893.
The last decades have witnessed a major advancement and development in three-dimensional (3D) printing technology. In the future, the trend's utilization of 3D printing is expected to play an important role in the biomedical field. This work presents co-extrusion of the polylactic acid (PLA), its derivatives (sPLA), and chitosan with the aim of achieving filaments for printing 3D objects, such as biomedical tools or implants. The physicochemical and antimicrobial properties were evaluated using SEM, FT-IR, DSC, instrumental mechanical test, and based on the ASTM E2149 standard, respectively. The addition of chitosan in the PLA and sPLA filaments increased their porosity and decreased density. The FT-IR analysis showed that PLA and chitosan only formed a physical mixture after extrusion. The addition of chitosan caused deterioration of the mechanical properties of filaments, especially elongation at break and Young's modulus. The addition of chitosan to the filaments improved their ability to crystallize and provide their antimicrobial properties against and
在过去几十年里，三维（3D）打印技术取得了重大进展和发展。未来，3D打印技术的应用趋势有望在生物医学领域发挥重要作用。这项工作展示了聚乳酸（PLA）、其衍生物（sPLA）和壳聚糖的共挤出，目的是制造用于打印3D物体的细丝，如生物医学工具或植入物。分别使用扫描电子显微镜（SEM）、傅里叶变换红外光谱（FT-IR）、差示扫描量热法（DSC）、仪器机械测试，并基于ASTM E2149标准对其物理化学和抗菌性能进行了评估。在PLA和sPLA细丝中添加壳聚糖增加了它们的孔隙率并降低了密度。FT-IR分析表明，PLA和壳聚糖在挤出后仅形成了物理混合物。壳聚糖的添加导致细丝的机械性能下降，尤其是断裂伸长率和杨氏模量。向细丝中添加壳聚糖提高了它们的结晶能力，并赋予它们针对……的抗菌性能
