School of Science and Technology, The University of Georgia, Tbilisi, Georgia.
Department of Materials and Metallurgical Engineering, Amirkabir University of Technology, Tehran 1599637111, Iran.
Biomolecules. 2022 Jan 18;12(2):155. doi: 10.3390/biom12020155.
Chitosan is a biopolymer that is found in nature and is produced from chitin deacetylation. Chitosan has been studied thoroughly for multiple applications with an interdisciplinary approach. Antifungal antibacterial activities, mucoadhesion, non-toxicity, biodegradability, and biocompatibility are some of the unique characteristics of chitosan-based biomaterials. Moreover, chitosan is the only widely-used natural polysaccharide, and it is possible to chemically modify it for different applications and functions. In various fields, chitosan composite and compound manufacturing has acquired much interest in developing several promising products. Chitosan and its derivatives have gained attention universally in biomedical and pharmaceutical industries as a result of their desired characteristics. In the present mini-review, novel methods for preparing chitosan-containing materials for dental and implant engineering applications along with challenges and future perspectives are discussed.
壳聚糖是一种天然存在的生物聚合物,由壳聚糖脱乙酰化产生。壳聚糖因其具有抗真菌、抗菌活性、黏膜黏附性、无毒、可生物降解和生物相容性等独特特性,已被广泛研究并应用于多个领域。此外,壳聚糖是唯一广泛使用的天然多糖,可通过化学修饰用于不同的应用和功能。在各个领域,壳聚糖复合材料和化合物的制造在开发有前途的产品方面引起了广泛关注。由于具有理想的特性,壳聚糖及其衍生物在生物医学和制药行业受到了普遍关注。在本次小型综述中,讨论了用于牙科和植入物工程应用的含壳聚糖材料的新型制备方法以及面临的挑战和未来展望。