Department of Pediatrics, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan province, China.
Department of Women and Child Health, School of Public Health, Kunming Medical University, Kunming, Yunnan province, China.
Environ Pollut. 2020 Jan;256:113055. doi: 10.1016/j.envpol.2019.113055. Epub 2019 Sep 11.
Little is known about fine particulate matter (PM) exposure among pregnant women in rural China. This study aims to characterize exposure to PM among pregnant women in rural China, and investigate potential risk factors of personal exposure to PM. The data were obtained from a birth cohort study that enrolled 606 pregnant women in Xuanwei, a county known for its high rates of lung cancer. The personal exposure to PM was measured using small portable particulate monitors during each trimester of pregnancy. Participants were interviewed using structured questionnaires that sought information on risk factors of PM exposure. The daily exposure to PM among the pregnant women ranged from 19.68 to 97.08 μg/m (median = 26.08). Exposure to PM was higher in winter and autumn than other seasons (p < 0.05); higher during the day than during the night (p < 0.001); and greater during cooking hours than during the rest of the day (p < 0.001). Using a mixed effects model, domestic solid fuel for cooking (β = 1.75, p < 0.001), winter and autumn (β = 2.96, p < 0.001), cooking ≥ once per day (β = 1.58, p < 0.05), heating with coal (β = 1.69, p < 0.001), secondhand smoke exposure (β = 1.59, p < 0.001) and township 1(β = 2.39, p < 0.001) were identified as risk factors for personal exposure to PM of pregnant women throughout pregnancy. Indirect effects of season and township factors on personal PM exposure were mediated by heating, cooking and domestic fuel using. In conclusion, PM levels in Xuanwei exceeded WHO guidelines. Seasonal and township factors and individual behaviors like domestic solid fuel using for cooking, heating with coal and secondhand smoke exposure are associated with higher personal PM exposure among pregnant women in rural China.
在中国农村地区,有关孕妇细颗粒物(PM)暴露的信息知之甚少。本研究旨在描述中国农村孕妇的 PM 暴露情况,并探讨个人 PM 暴露的潜在危险因素。数据来自一项在宣威开展的出生队列研究,该研究纳入了 606 名孕妇,宣威是一个肺癌高发县。在每个孕期,使用小型便携式颗粒物监测仪来测量孕妇的个人 PM 暴露情况。通过结构式问卷对参与者进行访谈,以获取有关 PM 暴露危险因素的信息。孕妇的每日 PM 暴露量范围为 19.68 至 97.08μg/m(中位数=26.08μg/m)。冬季和秋季的 PM 暴露量高于其他季节(p<0.05);白天的 PM 暴露量高于夜间(p<0.001);烹饪时间的 PM 暴露量高于其他时间(p<0.001)。使用混合效应模型,烹饪用的固体燃料(β=1.75,p<0.001)、冬季和秋季(β=2.96,p<0.001)、每天烹饪≥1 次(β=1.58,p<0.05)、使用煤炭取暖(β=1.69,p<0.001)、二手烟暴露(β=1.59,p<0.001)和乡 1(β=2.39,p<0.001)被确定为整个孕期孕妇个人 PM 暴露的危险因素。季节和乡镇因素对个人 PM 暴露的间接影响通过取暖、烹饪和家用燃料的使用来介导。总之,宣威的 PM 水平超过了世卫组织的指导方针。季节和乡镇因素以及个体行为,如烹饪用的固体燃料、煤炭取暖和二手烟暴露,与中国农村孕妇的个人 PM 暴露量较高有关。