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2000-2015 年巴西热暴露与糖尿病住院治疗的相关性:一项全国性病例交叉研究。

Association between Heat Exposure and Hospitalization for Diabetes in Brazil during 2000-2015: A Nationwide Case-Crossover Study.

机构信息

School of Public Health and Management, Binzhou Medical University, Yantai, Shandong, China.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

出版信息

Environ Health Perspect. 2019 Nov;127(11):117005. doi: 10.1289/EHP5688. Epub 2019 Nov 20.

DOI:10.1289/EHP5688
PMID:31746643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6927500/
Abstract

BACKGROUND

Exposure to excessive heat, which will continue to increase with climate change, is associated with increased morbidity due to a range of noncommunicable diseases (NCDs). Whether this is true for diabetes is unknown.

OBJECTIVES

We aimed to quantify the relationship between heat exposure and risk of hospitalization due to diabetes in Brazil.

METHODS

Data on hospitalizations and weather conditions were collected from 1,814 cities during the hot seasons from 2000 to 2015. A time-stratified case-crossover design was used to quantify the association between hospitalization for diabetes and heat exposure. Region-specific odds ratios (ORs) were used to calculate the attributable fractions (AFs).

RESULTS

A total of 553,351 hospitalizations associated with diabetes were recorded during 2000-2015. Every 5°C increase in daily mean temperature was associated with 6% [; 95% confidence interval (CI): 1.04, 1.07] increase in hospitalization due to diabetes with lag 0-3 d. The association was greatest (; 95% CI: 1.13, 1.23) in those of age, but did not vary by sex, and was generally consistent by region and type of diabetes. Assuming a causal association, we estimated that 7.3% (95% CI: 3.5, 10.9) of all hospitalizations due to diabetes in the hot season could be attributed to heat exposure during the study period.

DISCUSSION

Short-term heat exposure may increase the burden of diabetes-related hospitalization, especially among the very elderly. As global temperatures continue to rise, this burden is likely to increase. https://doi.org/10.1289/EHP5688.

摘要

背景

随着气候变化,暴露于过热环境中会增加一系列非传染性疾病(NCDs)导致的发病率。但这种情况是否适用于糖尿病尚不清楚。

目的

我们旨在量化热暴露与巴西因糖尿病住院风险之间的关系。

方法

本研究收集了 2000 年至 2015 年热季期间 1814 个城市的住院数据和天气状况。采用时间分层病例交叉设计来量化因糖尿病住院与热暴露之间的关联。使用特定区域的比值比(ORs)计算归因分数(AFs)。

结果

2000-2015 年期间共记录了 553351 例与糖尿病相关的住院病例。每日平均温度每升高 5°C,与糖尿病住院相关的风险增加 6%[95%置信区间(CI):1.04,1.07],滞后 0-3 天。这种关联在年龄为 的人群中最大[95% CI:1.13,1.23],但与性别无关,并且在不同地区和糖尿病类型之间基本一致。假设存在因果关系,我们估计在研究期间,热暴露导致的热季中所有因糖尿病住院的病例中有 7.3%(95% CI:3.5,10.9)可归因于热暴露。

讨论

短期热暴露可能会增加与糖尿病相关的住院负担,尤其是在非常年长的人群中。随着全球气温持续上升,这种负担可能会增加。https://doi.org/10.1289/EHP5688.

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