Foltin R W, Fischman M W
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Pharmacol Biochem Behav. 1988 Jun;30(2):539-41. doi: 10.1016/0091-3057(88)90494-7.
Six adult male research volunteers, in two groups of three subjects each, lived continuously in a residential laboratory for seven consecutive days. Subjects' behaviors, including social interaction and coaction, were continuously recorded. During the first part of the day (0945-1700), subjects remained in their private rooms doing work activities. During the remainder of the day (1700-2345), they had the option to socialize with the other subjects. Four cigarettes containing active marijuana (2.7% delta 9-THC w/w) or placebo were smoked daily: two during the work period, and two during the social access period. Active marijuana had no effect on the total amount of time that subjects spent in the social area. However, active marijuana changed the distribution of activity within the social area by decreasing the amount of time subjects spent engaging in verbal exchanges, i.e., interaction, while simultaneously increasing the amount of time that subjects engaged in the same activity, but in the absence of verbal exchanges, i.e., coaction.
六名成年男性研究志愿者,分为两组,每组三人,在一个住宅实验室中连续居住七天。对受试者的行为,包括社交互动和共同行动,进行持续记录。在一天的前半段时间(0945 - 1700),受试者待在自己的私人房间里进行工作活动。在一天的其余时间(1700 - 2345),他们可以选择与其他受试者进行社交。每天吸食四支含有活性大麻(2.7% δ9 - 四氢大麻酚,重量/重量)或安慰剂的香烟:两支在工作期间吸食,两支在社交时间段吸食。活性大麻对受试者在社交区域花费的总时间没有影响。然而,活性大麻改变了社交区域内活动的分布,减少了受试者进行言语交流(即互动)所花费的时间,同时增加了受试者在不进行言语交流(即共同行动)的情况下进行相同活动所花费的时间。