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糖尿病视网膜病变治疗新观念。

Emerging Concepts in the Treatment of Diabetic Retinopathy.

机构信息

Department of Ophthalmology and Vision Science, University of California Davis, 4860 Y Street Suite 2400, Sacramento, CA, 95817, USA.

California Northstate University College of Medicine, 9700 W Taron Drive, Elk Grove, CA, 95757, USA.

出版信息

Curr Diab Rep. 2019 Nov 20;19(11):137. doi: 10.1007/s11892-019-1276-5.

Abstract

PURPOSE OF REVIEW

Diabetic retinopathy (DR) is the leading cause of vision loss in working-age adults in the developed world. This review discusses the current approach to managing the disease, such as glycemic and blood pressure control, as well as laser photocoagulation, as well as emerging concepts and controversies on novel therapies.

RECENT FINDINGS

In recent years, the rise of intraocular anti-angiogenesis treatments is changing the paradigm of classic laser photocoagulation in the management of DR, but its long-term benefits remain an area of controversy. We also discuss new targets including anti-inflammation, neuroprotection, and novel laser technologies. Finally, we discuss new advances in retinal imaging that has vastly improved the diagnosis and management of DR. Diagnosis and management of diabetic retinopathy is a rapidly progressing field. Emerging concepts in ophthalmic imaging, medical treatments, and surgical approaches provide insights into how DR management will evolve in the near future.

摘要

目的综述

糖尿病视网膜病变(DR)是发达世界导致工作年龄段成年人视力丧失的主要原因。本文讨论了疾病的当前治疗方法,如血糖和血压控制以及激光光凝,以及新型治疗方法的新兴概念和争议。

最近的发现

近年来,眼内抗血管生成治疗的兴起正在改变 DR 管理中经典激光光凝的模式,但它的长期益处仍是一个有争议的领域。我们还讨论了新的靶点,包括抗炎、神经保护和新型激光技术。最后,我们讨论了视网膜成像的新进展,这大大改善了 DR 的诊断和管理。糖尿病视网膜病变的诊断和管理是一个快速发展的领域。眼科成像、医疗和手术方法方面的新观念提供了有关 DR 管理在不久的将来如何发展的见解。

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