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成人HIV阳性患者晚期伯基特淋巴瘤的罕见并发症及高剂量化疗成功治疗

Unusual complication and successful high-dose chemotherapy treatment of advanced Burkitt's lymphoma in an adult HIV-positive patient.

作者信息

McGrath Henrietta W H, Fitzhugh Alexander, Javed Maria, Rockwood Neesha, Kazmi Farhat

机构信息

Department of Radiology, Chelsea and Westminster Hospital, United Kingdom.

Department of Infectious Diseases and HIV, Chelsea and Westminster Hospital, United Kingdom.

出版信息

SA J Radiol. 2017 Nov 14;21(2):1230. doi: 10.4102/sajr.v21i2.1230. eCollection 2017.

DOI:10.4102/sajr.v21i2.1230
PMID:31754479
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6837768/
Abstract

Adult Burkitt's lymphoma emerged as an AIDS-defining condition in the 1980s. We describe a case of HIV-associated adult Burkitt's lymphoma diagnosed and treated with high-dose chemotherapy in our institution, complicated by unusual bilateral renal vein tumour thrombi and tumour lysis syndrome. We believe this unique case highlights the need for early recognition of current and potential complications on staging computed tomography imaging, as well as successful use of a high-dose chemotherapy regimen.

摘要

成人伯基特淋巴瘤在20世纪80年代成为一种艾滋病界定疾病。我们描述了一例在我们机构诊断并接受高剂量化疗的HIV相关成人伯基特淋巴瘤病例,该病例并发罕见的双侧肾静脉肿瘤血栓和肿瘤溶解综合征。我们认为这一独特病例凸显了在分期计算机断层扫描成像时早期识别当前和潜在并发症的必要性,以及高剂量化疗方案的成功应用。

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Unusual complication and successful high-dose chemotherapy treatment of advanced Burkitt's lymphoma in an adult HIV-positive patient.成人HIV阳性患者晚期伯基特淋巴瘤的罕见并发症及高剂量化疗成功治疗
SA J Radiol. 2017 Nov 14;21(2):1230. doi: 10.4102/sajr.v21i2.1230. eCollection 2017.
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本文引用的文献

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Adding rituximab to CODOX-M/IVAC chemotherapy in the treatment of HIV-associated Burkitt lymphoma is safe when used with concurrent combination antiretroviral therapy.在接受联合抗逆转录病毒治疗的同时,将利妥昔单抗添加到CODOX-M/IVAC化疗方案中用于治疗HIV相关的伯基特淋巴瘤是安全的。
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