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[利多卡因治疗紫杉叶(欧洲红豆杉)中毒]

[Lidocaine treatment of poisoning with yew needles (Taxus baccata L.)].

作者信息

von Dach B, Streuli R A

机构信息

Medizinische Abteilung, Regionalspital Langenthal.

出版信息

Schweiz Med Wochenschr. 1988 Jul 30;118(30):1113-6.

PMID:3175564
Abstract

A 40-year-old patient attempted suicide by drinking an extract made from 120 g of yew needles. Shortly after severe ventricular arrhythmia occurred characterized by extremely prolonged QRS-intervals. Recurrent episodes of ventricular tachycardia were successfully treated with high doses of lidocaine. In most cases intoxication by yew needles ends fatally. Lidocaine may be the drug of choice to treat life-threatening tachyarrhythmia in such cases.

摘要

一名40岁的患者饮用了从120克紫杉针叶中提取的汁液企图自杀。不久后出现严重的室性心律失常,其特征为QRS间期极度延长。多次室性心动过速发作经大剂量利多卡因成功治疗。在大多数情况下,紫杉针叶中毒会导致死亡。在这种情况下,利多卡因可能是治疗危及生命的快速性心律失常的首选药物。

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1
[Lidocaine treatment of poisoning with yew needles (Taxus baccata L.)].[利多卡因治疗紫杉叶(欧洲红豆杉)中毒]
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Eight cases of fatal and non-fatal poisoning with Taxus baccata.8 例红豆杉致命和非致命中毒。
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Extracorporeal life support and digoxin-specific Fab fragments for successful management of Taxus baccata intoxication with low output and ventricular arrhythmia.体外生命支持和地高辛特异性Fab片段成功治疗欧洲红豆杉中毒伴低心输出量和室性心律失常。
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[2 cases of lidocaine-resistant ventricular tachycardia treated with i.v. mexiletine during complicated acute myocardial infarct].
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Intoxication with taxus baccata: cardiac arrhythmias following yew leaves ingestion.欧洲红豆杉中毒:摄入紫杉树叶后出现心律失常。
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Post-mortem findings in 22 fatal Taxus baccata intoxications and a possible solution to its detection.22例欧洲红豆杉致命中毒的尸检结果及其检测的一种可能解决方案。
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[Lethal intoxication with leaves of the yew tree (Taxus baccata) (author's transl)].红豆杉(欧洲红豆杉)树叶致死性中毒(作者译)
Arch Toxicol. 1975 Oct 20;34(2):153-8. doi: 10.1007/BF00353316.

引用本文的文献

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A comparative study of five fatal cases of Taxus poisoning.五例红豆杉中毒致死病例的对比研究。
Int J Legal Med. 2007 Sep;121(5):417-22. doi: 10.1007/s00414-006-0099-5. Epub 2006 May 6.
2
[Psychiatric aspects of plant poisonings].[植物中毒的精神科问题]
Nervenarzt. 2005 Jul;76(7):875-6, 877-8. doi: 10.1007/s00115-005-1912-y.
3
Suicidal yew leave ingestion--phloroglucindimethylether (3,5-dimethoxyphenol) as a marker for poisoning from Taxus baccata.自杀性摄入紫杉树叶——间苯三酚二甲醚(3,5 - 二甲氧基苯酚)作为欧洲红豆杉中毒的标志物
Int J Legal Med. 1993;106(1):45-50. doi: 10.1007/BF01225024.
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Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs.心脏钠通道的阻断。通透离子与抗心律失常药物之间的竞争。
J Clin Invest. 1992 Aug;90(2):368-81. doi: 10.1172/JCI115871.