Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Molecules. 2019 Nov 20;24(23):4224. doi: 10.3390/molecules24234224.
An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.
已开发出一种有效的氨基酸保护和构建七元环的方法。该方法使用咪唑鎓氯化物在低温下进行迈克尔加成反应，并在高温下进行氨基脱保护或构建七元环。
