Food College, Northeast Agricultural University, No. 600 Changjiang St. Xiangfang Dist, 150030 Harbin, China; Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, No. 600 Changjiang St. Xiangfang Dist, 150030 Harbin, China.
Food College, Northeast Agricultural University, No. 600 Changjiang St. Xiangfang Dist, 150030 Harbin, China; Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, No. 600 Changjiang St. Xiangfang Dist, 150030 Harbin, China.
Food Chem. 2020 Apr 25;310:125865. doi: 10.1016/j.foodchem.2019.125865. Epub 2019 Nov 9.
Although infant formula represents an important human milk substitute, it has been shown to contain many different lipid structures compared to human milk. In this study, the lipidome and fatty acid composition of human, bovine and caprine milk were analyzed and compared. A total of 13 lipid classes (including TG, DG, SM, PC, Cer, HexCer, HexCer, PE, PG, PS, PI, PA and CL) were analyzed. Human milk was richer in TG containing LA, SM containing ULCFA and PLs containing ARA, DHA and DGLA. Moreover, there were no differential DG and SM species between human and caprine milk. A total of 215 and 147 lipids were identified as potential biomarkers that could be used to further analyze differences in the biological properties of human, bovine and caprine milk. This comprehensive analysis will hopefully help in the design of infant formula more suitable for Chinese babies.
虽然婴儿配方奶粉是一种重要的母乳代用品，但与母乳相比，它含有许多不同的脂质结构。在这项研究中，分析和比较了人乳、牛乳和羊乳的脂质组和脂肪酸组成。共分析了 13 种脂质类（包括 TG、DG、SM、PC、Cer、HexCer、HexCer、PE、PG、PS、PI、PA 和 CL）。人乳中含有更多的 LA 含量的 TG、富含 ULCFA 的 SM 和含有 ARA、DHA 和 DGLA 的 PL。此外，人乳和羊乳中没有差异的 DG 和 SM 种类。共鉴定出 215 种和 147 种脂质作为潜在的生物标志物，可用于进一步分析人乳、牛乳和羊乳生物学特性的差异。这项综合分析有望有助于设计更适合中国婴儿的婴儿配方奶粉。
