Clermont Auvergne University, EA 3533, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), 3 rue de la Chebarde, 63000 Clermont-Ferrand, France; CRNH-Auvergne, Rue Montablembert, 63000 Clermont-Ferrand, France; School of Psychology, Faculty of Medicine and Health, University of Leeds, Leeds, LS2 9JT, UK.
CRNH-Auvergne, Rue Montablembert, 63000 Clermont-Ferrand, France; Department of Sport Medicine and Functional Explorations, Clermont-Ferrand University Hospital, G. Montpied Hospital, Rue Montablembert, 63000 Clermont-Ferrand, France; University Clermont Auvergne, UFR Medicine, Rue Montablembert, 63000 Clermont-Ferrand, France; INRA, UMR 1019, Rue Montablembert, 63000 Clermont-Ferrand, France.
Physiol Behav. 2020 Feb 1;214:112744. doi: 10.1016/j.physbeh.2019.112744. Epub 2019 Nov 22.
The present study compared the appetite responses to an inpatient eccentric vs. concentric cycling training programs in adolescents with obesity.
24 adolescents with obesity (12-16yrs; Tanner 3-4) followed a 12-week multidisciplinary intervention (Phase1), after which they were randomized to concentric (CON) or eccentric (ECC) training for 12 weeks (Phase2). Assessment of anthropometrics, body composition (DXA), aerobic power (VO), energy (EI) and macronutrient intake, food reward, and subjective appetite were performed at baseline, and after Phase1 (T1) and Phase2 (T2).
Body mass, BMI, and fat mass (FM%) decreased in both groups (p < 0.001). FM% reduction was greater in ECC at T2 (-9.9%). EI did not change in either group at T1, but was greater at T2 relative to T1 in CON only (p < 0.001,+22%). There was no correlation between the change in body mass, FM%, fat-free mass and EI. Hunger (p = 0.002) and desire to eat (p = 0.001) were higher in CON vs. ECC with no time effects nor interactions. Prospective food consumption increased in both groups with no group effect nor interaction. Satiety was not different between groups or over time. In ECC, preference for high-fat foods increased (p = 0.03), and preference (p = 0.004) and implicit wanting (p = 0.016) for sweet foods decreased.
Eccentric cycling as part of an inpatient multidisciplinary weight-loss intervention might help prevent increased ad libitum energy intake compared to concentric exercise training in adolescents with obesity, potentially through distinct effects of the food reward system.
本研究比较了肥胖青少年住院期间进行离心与向心自行车训练计划的食欲反应。
24 名肥胖青少年（12-16 岁；Tanner 3-4 期）接受了 12 周的多学科干预（第 1 阶段），之后他们被随机分为向心（CON）或离心（ECC）训练 12 周（第 2 阶段）。在基线、第 1 阶段（T1）和第 2 阶段（T2）时，评估了人体测量学、身体成分（DXA）、有氧能力（VO）、能量（EI）和宏量营养素摄入、食物奖励和主观食欲。
两组体重、BMI 和脂肪量（FM%）均降低（p<0.001）。ECC 在 T2 时 FM%的减少更大（-9.9%）。在第 1 阶段，两组的 EI 均未发生变化，但仅在 CON 组中 T2 相对于 T1 有所增加（p<0.001，增加 22%）。体重、FM%、瘦体重的变化与 EI 之间无相关性。CON 组的饥饿感（p=0.002）和食欲（p=0.001）均高于 ECC 组，且无时间效应或交互作用。两组的预期食物摄入量均增加，且无组间效应或交互作用。CON 组和 ECC 组的饱腹感无差异。ECC 组对高脂肪食物的偏好增加（p=0.03），对甜食的偏好（p=0.004）和隐性欲望（p=0.016）下降。
作为住院多学科减肥干预的一部分，离心自行车运动可能有助于预防肥胖青少年与向心运动训练相比，自由摄入能量增加，这可能是通过食物奖励系统的不同作用。
