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营养缺乏症的神经病学。

Neurology of Nutritional Deficiencies.

机构信息

Department of Neurology and Rehabilitation, University of Illinois at Chicago College of Medicine, 912 S Wood St, Chicago, IL, 60612, USA.

出版信息

Curr Neurol Neurosci Rep. 2019 Nov 26;19(12):101. doi: 10.1007/s11910-019-1011-2.

DOI:10.1007/s11910-019-1011-2
PMID:31773293
Abstract

PURPOSE OF REVIEW

The goal of this chapter is to educate clinicians on the neurologic manifestations of certain nutritional deficiencies in order to promptly identify and appropriately treat these patients.

RECENT FINDINGS

Many vitamin and nutritional deficiencies have been described dating back to the early days of neurology and medicine. Some are very rare and thus, there are no randomized controlled studies to assess supplementation or dosage; however, there are reviews of case reports that can assist clinicians in choosing treatments. While endemic vitamin and nutritional deficiencies may be rarely encountered in many countries, vulnerable populations continue to be at risk for developing neurologic complications. These populations include those with diseases causing malabsorption, the elderly, chronic alcohol users, as well as pregnant mothers with hyperemesis gravidarum to name a few. It is important to recognize syndromes associated with these nutritional deficiencies, as prompt identification and treatment may prevent permanent neurologic damage.

摘要

目的综述

本章旨在教育临床医生了解某些营养缺乏症的神经表现,以便及时识别和适当治疗这些患者。

最新发现

自神经病学和医学早期以来,已有许多维生素和营养缺乏症被描述。有些非常罕见,因此没有随机对照研究来评估补充剂或剂量;然而,有病例报告的综述可以帮助临床医生选择治疗方法。虽然在许多国家,地方性维生素和营养缺乏症很少见,但弱势群体仍有发生神经并发症的风险。这些人群包括患有吸收不良疾病、老年人、慢性酒精使用者以及妊娠剧吐的孕妇等。重要的是要认识到与这些营养缺乏症相关的综合征,因为及时识别和治疗可能预防永久性神经损伤。

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Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications.烟酸在中枢神经系统中的作用:生物学方面和临床应用的更新。
Int J Mol Sci. 2019 Feb 23;20(4):974. doi: 10.3390/ijms20040974.
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Controversies in Vitamin D: Summary Statement From an International Conference.维生素 D 争议:国际会议总结声明。
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Rapidly Resolving Nonalcoholic Marchiafava-Bignami Disease in the Setting of Malnourishment After Gastric Bypass Surgery.
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Vitamin B₆ and Its Role in Cell Metabolism and Physiology.维生素B₆及其在细胞代谢和生理学中的作用。
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Oral vitamin B versus intramuscular vitamin B for vitamin B deficiency.口服维生素B与肌肉注射维生素B治疗维生素B缺乏症的比较
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The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function.维生素 B6 悖论:高浓度吡哆醇(维生素 B6 的一种形式)的补充会导致维生素 B6 功能降低。
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Many tocopherols, one vitamin E.许多生育酚,一种维生素 E。
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Vitamin B Intake and the Risk of Colorectal Cancer: A Meta-Analysis of Prospective Cohort Studies.维生素B摄入量与结直肠癌风险:前瞻性队列研究的荟萃分析
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