Department of Neurology and Rehabilitation, University of Illinois at Chicago College of Medicine, 912 S Wood St, Chicago, IL, 60612, USA.
Curr Neurol Neurosci Rep. 2019 Nov 26;19(12):101. doi: 10.1007/s11910-019-1011-2.
The goal of this chapter is to educate clinicians on the neurologic manifestations of certain nutritional deficiencies in order to promptly identify and appropriately treat these patients.
Many vitamin and nutritional deficiencies have been described dating back to the early days of neurology and medicine. Some are very rare and thus, there are no randomized controlled studies to assess supplementation or dosage; however, there are reviews of case reports that can assist clinicians in choosing treatments. While endemic vitamin and nutritional deficiencies may be rarely encountered in many countries, vulnerable populations continue to be at risk for developing neurologic complications. These populations include those with diseases causing malabsorption, the elderly, chronic alcohol users, as well as pregnant mothers with hyperemesis gravidarum to name a few. It is important to recognize syndromes associated with these nutritional deficiencies, as prompt identification and treatment may prevent permanent neurologic damage.
本章旨在教育临床医生了解某些营养缺乏症的神经表现,以便及时识别和适当治疗这些患者。
自神经病学和医学早期以来,已有许多维生素和营养缺乏症被描述。有些非常罕见,因此没有随机对照研究来评估补充剂或剂量;然而,有病例报告的综述可以帮助临床医生选择治疗方法。虽然在许多国家,地方性维生素和营养缺乏症很少见,但弱势群体仍有发生神经并发症的风险。这些人群包括患有吸收不良疾病、老年人、慢性酒精使用者以及妊娠剧吐的孕妇等。重要的是要认识到与这些营养缺乏症相关的综合征,因为及时识别和治疗可能预防永久性神经损伤。