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电针或艾灸“天枢”(ST25)对大鼠胃内压的影响

[Effect of electroacupuncture or moxibustion of "Tianshu" (ST25) on intragastric pressure in rats].

作者信息

Li Wen, Lu Meng-Jiang, Yu Zhi, Han Xu, He Yan, Xu Bin

机构信息

Key Laboratory of Integrated Acupuncture and Drugs of Chinese Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China.

出版信息

Zhen Ci Yan Jiu. 2019 Nov 25;44(11):822-5. doi: 10.13702/j.1000-0607.190025.

DOI:10.13702/j.1000-0607.190025
PMID:31777232
Abstract

OBJECTIVE

To observe the effect of electroacupunctur (EA) and moxibustion of left or right "Tian-shu" (ST25) on intragastric pressure (IGP) in normal rats.

METHODS

Twenty male SD rats were equally and randomly divided into EA group and moxibustion group. EA (2 Hz/15 Hz, 2 mA) or moxibustion (46-48 ℃) was applied to unilate-ral ST25 for 2 min. The IGP was detected by using a pressure-transducer and an amplifier before and after EA or moxibustion.

RESULTS

Compared with pre-intervention, the IGP was significantly decreased after EA or moxibustion stimulation of both left and right ST25 (<0.05). The IGP levels during 0-30 s and 30-60 s of EA stimulation of both left and right ST25 were significantly lower than those of moxibustion (<0.05). The IGP-lowering effect of EA on the left ST25 was evidently stronger than that of the right ST25 (<0.05), but without significant difference between the bilateral sides in moxibustion-induced IGP reduction (>0.05).

CONCLUSION

Both EA and moxibustion of ST25 can lower IGP, and the effect of EA is significantly stronger than that of moxibustion in normal rats. In addition, the IGP-lowering effect of EA of the left ST25 is markedly stronger than that of the right ST25, suggesting a lateral advantage effect.

摘要

目的

观察电针及艾灸左侧或右侧“天枢”(ST25)对正常大鼠胃内压(IGP)的影响。

方法

将20只雄性SD大鼠平均随机分为电针组和艾灸组。对单侧ST25施加电针(2Hz/15Hz,2mA)或艾灸(46 - 48℃)2分钟。在电针或艾灸前后,使用压力传感器和放大器检测胃内压。

结果

与干预前相比,电针或艾灸双侧ST25后胃内压均显著降低(<0.05)。电针刺激双侧ST25在0 - 30秒和30 - 60秒期间的胃内压水平显著低于艾灸(<0.05)。电针对左侧ST25的降胃内压作用明显强于右侧ST25(<0.05),但艾灸引起的双侧胃内压降低之间无显著差异(>0.05)。

结论

ST25电针和艾灸均可降低胃内压,在正常大鼠中电针效果明显强于艾灸。此外,左侧ST25电针的降胃内压作用明显强于右侧ST25,提示存在侧优势效应。

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