Zhao Haixia, Yang Zhaoping, Han Xiaotong, Guan Wenying, Wang Zhaoge, Cai Meilan, Sun Yi, Ge Ruichun, Wang Ruifang
Department of Ophthalmology, The Affiliated Hospital of Inner Mongolia Medical University, Huhhot 010050, China.
Arq Bras Oftalmol. 2020 Mar-Apr;83(2):92-97. doi: 10.5935/0004-2749.20200015.
To analyze subclinical keratoconus topography indexes using Pentacam and Orbscan-II measurements to identify evidences for seeking sensitive indexes to screen and diagnose subclinical keratoconus.
Fifty healthy participants (50 eyes) and 40 patients with subclinical keratoconus (40 eyes) were included. Seven common parameters including corneal thickness at the thinnest point; minimum curvature of the front surface (minimum simulated keratometry value, SimK's Min); maximum curvature of the front surface (maximum simulated keratometry value, SimK's Max); the frontal corneal surface best-fit spherical radius of the curvature; the back corneal surface best-fit spherical radius of curvature; the anterior corneal surface height (anterior Diff value); and the posterior corneal surface height (posterior Diff value) measured by Pentacam and Orbscan-II between normal and subclinical keratoconus eyes were compared.
Statistical differences between the healthy and subclinical keratoconus groups (p<0.01) were found in all corneal parameters measured using both devices. Differences in the minimum curvature of the front surface (SimK's Min), thinnest point, anterior Diff value, and posterior Diff value were significant between Pentacam and Orbscan-II in the subclinical keratoconus group (p<0.05).
The findings of this study identify the differences between normal and subclinical keratoconus eyes at the minimum curvature of the front surface, maximum curvature of the front surface, frontal corneal surface best-fit spherical radius of curvature, back corneal surface best-fit spherical radius of curvature, Anterior Diff value, and Posterior Diff value measures using Orbscan II and Pentacam that can help eye care practitioners clinically diagnose subclinical keratoconus.
使用Pentacam和Orbscan-II测量分析亚临床圆锥角膜的地形图指数,以寻找敏感指数用于亚临床圆锥角膜筛查和诊断。
纳入50名健康受试者(50只眼)和40例亚临床圆锥角膜患者(40只眼)。比较Pentacam和Orbscan-II测量的7个常见参数,包括最薄点处角膜厚度、前表面最小曲率(最小模拟角膜曲率值,SimK's Min)、前表面最大曲率(最大模拟角膜曲率值,SimK's Max)、前角膜表面最佳拟合球面曲率半径、后角膜表面最佳拟合球面曲率半径、前角膜表面高度(前Diff值)和后角膜表面高度(后Diff值)在正常眼和亚临床圆锥角膜眼之间的差异。
使用两种设备测量的所有角膜参数在健康组和亚临床圆锥角膜组之间均存在统计学差异(p<0.01)。在亚临床圆锥角膜组中,Pentacam和Orbscan-II在前表面最小曲率(SimK's Min)、最薄点、前Diff值和后Diff值方面存在显著差异(p<0.05)。
本研究结果确定了使用Orbscan II和Pentacam测量的前表面最小曲率、前表面最大曲率、前角膜表面最佳拟合球面曲率半径、后角膜表面最佳拟合球面曲率半径、前Diff值和后Diff值在正常眼和亚临床圆锥角膜眼之间的差异,这有助于眼科医生临床诊断亚临床圆锥角膜。