School of Public Health, University of Alberta, 2-040 Li Ka Shing Center for Health Research Innovation, Edmonton, AB, T6G 2E1, Canada.
Faculty of Rehabilitation Medicine, University of Alberta, 3-44 Corbett Hall, Edmonton, AB, T6G 2G4, Canada.
Health Qual Life Outcomes. 2019 Nov 29;17(1):176. doi: 10.1186/s12955-019-1243-5.
To examine the association between individual-level deprivation and health-related quality of life (HRQL) in the general population.
Data from a population-based survey in the Canadian province of Alberta were used. Individual-level deprivation was assessed using the Canadian Deprivation Index (CDI) and the Ontario Deprivation Index (ODI). HRQL was assessed using the EQ-5D-5 L. Differences in problems in the EQ-5D-5 L dimensions, index and visual analogue scale (VAS) scores across levels of deprivation were examined. Multivariate logistic and linear regression models adjusted for socio-demographic and other characteristics were used to examine the independent association between deprivation and HRQL.
Of the 6314 respondents, 39% were aged between 18 and 44 years and 38% between 45 and 64 years; 60% were female. Mean EQ-5D-5 L index and VAS scores were 0.85 (standard deviation [SD] 0.14) and 79.6 (SD 17.7), respectively. Almost one-third (30.6%) of respondents reported no problems on all EQ-5D-5 L dimensions. Few participants reported some problems with mobility (23.8%), self-care (6.2%) and usual activities (25.2%), while 59.3 and 35.5% reported some levels of pain/discomfort and anxiety/depression, respectively. Differences between the most and least deprived in reporting problems in EQ-5D-5 L dimensions, index and VAS scores were statistically significant and clinically important. In adjusted regression models for both deprivation indices, the least well-off, compared to the most well-off, had higher likelihood of reporting problems in all EQ-5D-5 L dimensions. Compared to the most well-off, the least well-off had an EQ-5D-5 L index score decrement of 0.18 (p < 0.01) and 0.17 (p < 0.01) for the CDI and ODI, respectively. Similarly, an inverse association was found between the VAS score and the CDI (β = - 17.3, p < 0.01) as well as the ODI (β = - 13.3, p < 0.01).
Individual-level deprivation is associated with worse HRQL. Poverty reduction strategies should consider the effects of not only neighbourhood-level deprivation, but also that of individual-level deprivation to improve overall health.
研究人群中个体贫困与健康相关生活质量(HRQL)之间的关联。
使用加拿大艾伯塔省一项基于人群的调查数据。个体贫困程度采用加拿大贫困指数(CDI)和安大略贫困指数(ODI)进行评估。HRQL 采用 EQ-5D-5L 进行评估。根据贫困程度,分析 EQ-5D-5L 维度、指数和视觉模拟量表(VAS)评分的差异。采用调整社会人口学和其他特征的多变量逻辑回归和线性回归模型,分析贫困与 HRQL 之间的独立关联。
在 6314 名受访者中,39%的年龄在 18 至 44 岁之间,38%的年龄在 45 至 64 岁之间;60%为女性。EQ-5D-5L 指数和 VAS 评分的平均值分别为 0.85(标准差 [SD] 0.14)和 79.6(SD 17.7)。近三分之一(30.6%)的受访者在所有 EQ-5D-5L 维度上均无问题。很少有参与者报告在移动性(23.8%)、自理能力(6.2%)和日常活动(25.2%)方面存在一些问题,而 59.3%和 35.5%分别报告存在一定程度的疼痛/不适和焦虑/抑郁。在 EQ-5D-5L 维度、指数和 VAS 评分报告方面,最贫困和最富裕人群之间的差异在统计学上和临床上均有显著意义。在调整后的两个贫困指数的回归模型中,与最富裕人群相比,最贫困人群在所有 EQ-5D-5L 维度上报告存在问题的可能性更高。与最富裕人群相比,CDI 和 ODI 得分分别下降 0.18(p<0.01)和 0.17(p<0.01)。同样,VAS 评分与 CDI(β=-17.3,p<0.01)和 ODI(β=-13.3,p<0.01)呈负相关。
个体贫困与较差的 HRQL 相关。减贫战略不仅应考虑到社区层面的贫困,还应考虑到个体层面的贫困,以改善整体健康状况。