Dreno B, Shourick J, Kerob D, Bouloc A, Taïeb C
Department of Dermato-Cancerology, CHU Nantes-Hôtel-Dieu CRCINA, Inserm 1232, CIC 1413, University of Nantes, Nantes, France.
Bio Informatics/statistics, University of Paris Sud, Paris, France.
J Eur Acad Dermatol Venereol. 2020 May;34(5):1057-1064. doi: 10.1111/jdv.16119. Epub 2020 Feb 13.
Acne severity and its response to treatment may be influenced by internal and external factors: the exposome.
The aim of this international real-life survey was to assess the most involved exposome factors in acne.
Eleven thousand individuals, aged between 15 and 39 years, with clinically confirmed acne or without acne, defined by age, gender and prevalence, were invited to participate in an Internet survey of 63 questions in order to assess the frequency of identified acne exposome factors.
Data from 6679 questionnaires were used for statistical analysis purposes: 2826 from the acne group and 3853 from the control group. Nibbling, consumption of dairy products, sweets, alcohol or whey proteins, as well as exposure to pollution, stress, certain mechanical factors and humid or hot weather or sun exposure, were significantly (all P ≤ 0.05) more frequently reported for the acne group than for the control group. This was not the case for tobacco consumption. Data regarding the impact of cannabis consumption were insufficient for drawing any conclusions.
Data from this international, anonymized Internet questionnaire conducted with more than almost 6700 participants add new arguments to assumptions made that certain exposome factors have an impact on acne. Nutrition, pollution, stress and harsh skincare, as well as climate and sun exposure may be considered the most frequent factors related to acne.
痤疮严重程度及其对治疗的反应可能受到内部和外部因素（暴露组）的影响。
这项国际现实生活调查的目的是评估痤疮中最相关的暴露组因素。
邀请了11000名年龄在15至39岁之间、临床确诊患有痤疮或未患痤疮（根据年龄、性别和患病率确定）的个体参与一项包含63个问题的网络调查，以评估已确定的痤疮暴露组因素的出现频率。
6679份问卷的数据用于统计分析：痤疮组2826份，对照组3853份。痤疮组报告啃咬、食用乳制品、甜食、酒精或乳清蛋白，以及接触污染、压力、某些机械因素、潮湿或炎热天气或日晒的频率显著（所有P≤0.05）高于对照组。吸烟情况并非如此。关于大麻消费影响的数据不足以得出任何结论。
这项对近6700名参与者进行的国际匿名网络问卷数据为某些暴露组因素对痤疮有影响的假设增添了新的论据。营养、污染、压力和不当的皮肤护理，以及气候和日晒可能被认为是与痤疮相关的最常见因素。
